| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V67790 | 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid; 3-oxoLCA) | 1553-56-6 | 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits TH17 cell differentiation by directly binding to the key transcription factor RORγt (Kd=1.13 μM). |
|
V85431 | Antitumor agent-127 | ||
|
V2953 | GSK2981278 | 1474110-21-8 | GSK2981278 (GSK-2981278; GSK 2981278) is a novel, potent and selective inverse agonist of RORγ (retinoid-related orphan receptor gamma) with potential anti-inflammatory and immumomodulatory activity (e. |
|
V120224 | Hexyl 4-hydroxybenzoate | 1083-27-8 | Hexyl 4-hydroxybenzoic acid (hexyl p-hydroxybenzoate) is a retinoid-associated orphan receptor RORγ(t) agonist with an EC50 of 144 nM. |
|
V67805 | JNJ-61803534 | 1917306-14-9 | JNJ-61803534 is a potent, orally bioactive RORγt inverse agonist/activator with IC50 of 9.6 nM. |
|
V144294 | ROR1 ligand-1 | ROR1 ligand-1 is the ligand of PROTACT ROR1 degrader-1. | |
|
V144295 | ROR1-IN-2 | ROR1-IN-2 is a highly effective and selective ROR1 inhibitor. | |
|
V144296 | ROR1-IN-3 | ROR1-IN-3 is a highly potent and selective ROR1 kinase inhibitor (IC50 = 17.6 nM). | |
|
V67793 | RORγ agonist 1 | 2260631-91-0 | RORγ agonist 1 is a potent orally bioavailable RORγ agonist (EC50 = 21 nM) with anti-tumor effects. |
|
V144299 | RORγ agonist 2 | RORγ agonist 2 is a selective RORγ agonist with an EC50 of 0.03 μM for hRORγ. | |
|
V67795 | RORγt agonist 1 | 2377378-89-5 | RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist/activator with EC50 of 20.8 nM. |
|
V144300 | RORγt inhibitor 4 | 1426803-07-7 | RORγt inhibitor 4 is an orally effective RORγt inhibitor that can cross the blood-brain barrier. |
|
V105012 | RORγt inverse agonist 34 | 2247604-77-7 | RORγt inverse agonist 34 (compound 5a) is a RORγt inverse agonist that inhibits RORγt-LBD with an IC50 of 0.094 μM. |
|
V33196 | SR1001 | 1335106-03-0 | SR1001 (SR-1001) is a novel, potent and selective antagonist/inhibitor/inverse agonist of the nuclear retinoic acid receptor-related orphan receptorsRORα and RORγ with immunomodulatory effects. |
|
V7133 | TMP778 | 1422053-04-0 | TMP778 (TMP-778; TMP 778) is a novel and potent RORγt inverse agonist with potential anti-inflammatory activity. |