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ROR

ROR

ROR related products

Structure Cat No. Product Name CAS No. Product Description
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid; 3-oxoLCA) V67790 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid; 3-oxoLCA) 1553-56-6 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits TH17 cell differentiation by directly binding to the key transcription factor RORγt (Kd=1.13 μM).
Antitumor agent-127 V85431 Antitumor agent-127
GSK2981278 V2953 GSK2981278 1474110-21-8 GSK2981278 (GSK-2981278; GSK 2981278) is a novel, potent and selective inverse agonist of RORγ (retinoid-related orphan receptor gamma) with potential anti-inflammatory and immumomodulatory activity (e.
Hexyl 4-hydroxybenzoate V120224 Hexyl 4-hydroxybenzoate 1083-27-8 Hexyl 4-hydroxybenzoic acid (hexyl p-hydroxybenzoate) is a retinoid-associated orphan receptor RORγ(t) agonist with an EC50 of 144 nM.
JNJ-61803534 V67805 JNJ-61803534 1917306-14-9 JNJ-61803534 is a potent, orally bioactive RORγt inverse agonist/activator with IC50 of 9.6 nM.
ROR1 ligand-1 V144294 ROR1 ligand-1 ROR1 ligand-1 is the ligand of PROTACT ROR1 degrader-1.
ROR1-IN-2 V144295 ROR1-IN-2 ROR1-IN-2 is a highly effective and selective ROR1 inhibitor.
ROR1-IN-3 V144296 ROR1-IN-3 ROR1-IN-3 is a highly potent and selective ROR1 kinase inhibitor (IC50 = 17.6 nM).
RORγ agonist 1 V67793 RORγ agonist 1 2260631-91-0 RORγ agonist 1 is a potent orally bioavailable RORγ agonist (EC50 = 21 nM) with anti-tumor effects.
RORγ agonist 2 V144299 RORγ agonist 2 RORγ agonist 2 is a selective RORγ agonist with an EC50 of 0.03 μM for hRORγ.
RORγt agonist 1 V67795 RORγt agonist 1 2377378-89-5 RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist/activator with EC50 of 20.8 nM.
RORγt inhibitor 4 V144300 RORγt inhibitor 4 1426803-07-7 RORγt inhibitor 4 is an orally effective RORγt inhibitor that can cross the blood-brain barrier.
RORγt inverse agonist 34 V105012 RORγt inverse agonist 34 2247604-77-7 RORγt inverse agonist 34 (compound 5a) is a RORγt inverse agonist that inhibits RORγt-LBD with an IC50 of 0.094 μM.
SR1001 V33196 SR1001 1335106-03-0 SR1001 (SR-1001) is a novel, potent and selective antagonist/inhibitor/inverse agonist of the nuclear retinoic acid receptor-related orphan receptorsRORα and RORγ with immunomodulatory effects.
TMP778 V7133 TMP778 1422053-04-0 TMP778 (TMP-778; TMP 778) is a novel and potent RORγt inverse agonist with potential anti-inflammatory activity.
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