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ERK

ERK related products

Structure Cat No. Product Name CAS No. Product Description
(S)-IP-DK143 V122177 (S)-IP-DK143 (S)-IP-DK143 is a polymer micelle formulation.
AZD-0364 V3801 AZD-0364 2097416-76-5 AZD0364 is a potent and selective oral inhibitor of ERK1/2 that is efficacious in both monotherapy and combination therapy in models of NSCLC.
BAY885 V4176 BAY885 2307249-33-6 BAY-885 is a novel, highly potent and selective ERK5/MAPK7 inhibitor with IC50 of 40 nM.
BI-113823 V130132 BI-113823 1119282-90-4 BI-113823 is an orally effective bradykinin B1 receptor antagonist that crosses the blood-brain barrier, with a Ki value of 5.3 nM for human receptors and 13.3 nM for rat receptors.
DEL-22379 V0469 DEL-22379 181223-80-3 DEL-22379 is a novel, potent,selective, and water-soluble ERK (extracellular signal-related kinase 2) dimerization inhibitor with potential antitumor activity.
ERK-IN-7 V69832 ERK-IN-7 2494010-63-6 RK-IN-7 (Example 10) is an analog of SHR2415 and a potent ERK inhibitor (antagonist) with IC50s of 5 nM and 7 nM for ERK1 and ERK2, respectively.
FR 180204 V0465 FR 180204 865362-74-9 FR-180204 (FR180204) is a novel, potent, selectiveand ATP-competitive inhibitor of ERK (extracellular signal-regulated kinase) with potential anti-inflammatory activity and has the potential to be used as a new therapy for rheumatoid arthritis.
GDC-0994 V0466 Ravoxertinib (GDC-0994; RG-7842) 1453848-26-4 Ravoxertinib (formerly known as GDC0994; RG7842) is a novel, potent, orally bioavailable inhibitor of extracellular signal-regulated kinase (ERK1/2) with potential antineoplastic activity.
GP369 V136853 GP369 GP369 is a humanized FGFR2-IIIb specific antibody.
HDAC6-IN-61 V137203 HDAC6-IN-61 HDAC6-IN-61 is an HDAC6 inhibitor (IC50: 73 nM) that is selective for other HDAC isotypes.
HDAC6-IN-74 V137206 HDAC6-IN-74 HDAC6-IN-74 is an orally effective selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 value of 0.036 μM.
HYD-1 V137653 HYD-1 351327-13-4 HYD-1 is a D-amino acid tumor cell adhesion peptide.
MK-8353 V4122 MK-8353 1184173-73-6 MK-8353 (also known as SCH900353; SCH-900353) is a novel, potent, selective and orally bioavailable ERK inhibitor with anticancer activity.
Napyradiomycin B4 V87066 Napyradiomycin B4 Napyradiomycin B4 is a napyradiomycin derivative that inhibits RANKL-induced MEK-ERK signaling pathway.
PAK1-IN-2 V142148 PAK1-IN-2 PAK1-IN-2 is a selective PAK1 inhibitor with a Ki value of 7.3 nM.
Peptide R analogue 10 V142464 Peptide R analogue 10 1998129-59-1 Peptide R analogue 10 is an analogue of the CXCR4 antagonistic peptide Peptide R, with stronger antagonistic potency, specificity and plasma stability.
RM-046 V144222 RM-046 3058972-05-4 RM-046 is an orally effective selective KRASQ61H (active form) ternary complex inhibitor.
SAIT-301 V144518 SAIT-301 SAIT-301 is a monoclonal antibody that targets Met.
Salbutamol-d4 V144536 Salbutamol-d4 2517375-34-5 Salbutamol-d4 is deuterated salbutamol.
SCH772984 V0463 SCH772984 942183-80-4 SCH772984 (SCH-772984) is a novel, potent and ATP-competitive inhibitor of ERK1/2 with potential antitumor activity.
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