| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V73547 | (R)-Bromoenol lactone ((R,E)-Bromoenol lactone) | 478288-90-3 | (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase gamma (iPLA2γ). |
|
V3849 | ACA | 110683-10-8 | ACA [also known as N-(p-amylcinnamoyl) Anthranilic Acid] is a broad-spectrum inhibitor ofphospholipase A2 (PLA2) and a TRP channel blocker. |
|
V87683 | Brinazarone | 89622-90-2 | Brinazarone (SR 33287) is an acidic lysosomal sphingomyelinase inhibitor that causes intracellular lipid deposition. |
|
V2928 | CAY10650 | 1233706-88-1 | CAY10650 (CAY-10650) is a novel and highly potent inhibitor of cytosolic phospholipase A2α (cPLA2α) (IC50 = 12 nM) with anti-inflammatory activity. |
|
V87676 | Choline tosylate | 55357-38-5 | Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. |
|
V131728 | Cinatrin C1 | 136266-35-8 | Cinatrin C1 is a phospholipase A2 (PLA2) inhibitor that can be extracted from Circinotrichum falcatisporum RF-641. |
|
V0844 | Darapladib (SB-480848) | 356057-34-6 | Darapladib (formerly also known as SB-480848; SB 480848; SB480848),a substituted pyrimidone, is a novel, potent and reversible inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitorwith potential anti-inflammatory activity. |
|
V102976 | DPTIP hydrochloride | 2361799-64-4 | DPTIP hydrochloride is a potent and blood-brain permeable neutral sphingomyelinase (N-SMase 2) (exosome inhibitor) with IC50 of 30 nM. |
|
V2778 | GW-4869 HCl | 6823-69-4 | GW4869 HCl (GW-4869; GW-69A;GW-554869A), the dihydrochloride salt ofGW4869, is a neutral, cell permeable and noncompetitive inhibitor of sphingomyelinase (SMase) (IC50 = 1 μM) and is most widely used pharmacological agent for blocking exosome generation. |
|
V137287 | Heptanoyl thio-PC | Heptanoyl thio-PC is a sn-2 thiol-labeled phospholipase A2 (PLA2) substrate that can be used to detect phospholipase A2 activity. | |
|
V73528 | LEI-401 | 2393840-15-6 | LEI-401 is a first-in-class, selective, BBB (blood-brain barrier)-passing NAPE-PLD (N-acylphosphoethanolamine phospholipase D) inhibitor (antagonist) with IC50 of 27 nM. |
|
V115554 | ML114 | 866149-26-0 | ML114 is a specific RBBP9 serine hydrolase inhibitor with an IC50 value of 0.63 μM against recombinant RBBP9. |
|
V115481 | ML256 | 2415152-07-5 | ML256 is a covalently bound lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. |
|
V2945 | ML348 | 899713-86-1 | ML348 (also known as CID 3238952; SID 160654487) is a reversible inhibitor of LYPLA1 (Lysophospholipase 1) with an IC50 value of 210 nM. |
|
V4495 | ML349 | 890819-86-0 | ML349 (ML-349) is a novel, potent,reversible, highly selective and specificacyl protein thioesterase 2(APT-2) inhibitor with aKiof 120 nM. |
|
V80610 | nSMase2-IN-1 | 2968322-24-7 | nSMase2-IN-1 is an orally bioavailable neutral sphingomyelinase 2 (nSMase2) inhibitor (antagonist) with IC50 of 0.13 ± 0.06 μM. |
|
V142288 | PC(O-16:0/18:2(9Z,12Z)) | 88542-95-4 | PC(O-16:0/18:2(9Z,12Z)) is a phospholipid. |
|
V73549 | Pyrrophenone | 341973-06-6 | Pyrrophenone is a potent and specific inhibitor of cytosolic phospholipase A2α (cPLA2α) with IC50 of 4.2 nM. |
|
V145049 | SMases D-IN-1 | 849020-48-0 | SMases D-IN-1 is a sphingomyelinase D (SMase D) inhibitor derived from the hermit spider (brown hermit spider) with a Ki value of 0.54 μM. |
|
V87685 | Sphingolactone-24 | 881177-99-7 | Sphingolactone-24 (Sph-24) is a selective and irreversible inhibitor of neutral sphingomyelinase (nSMase). |
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