| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V7118 | A77-01 | 607737-87-1 | A 77-01 is a potent inhibitor of the TGF-β type I receptor family ALK5 with IC50 of 25 nM. |
|
V7153 | A83-01 | 909910-43-6 | A-83-01 is an ALK inhibibitor. |
|
V128263 | ActRIIB-IN-1 | 3039974-31-4 | ActRIIB-IN-1 is an orally effective activin type II receptor B (ActRIIB) inhibitor with an IC50 value of 1.8 nM. |
|
V128264 | ActRIIB-IN-2 | 3039974-32-5 | ActRIIB-IN-2 is an ActRIIB inhibitor with an IC50 of 1.1 nM. |
|
V129671 | Autotaxin-IN-7 | Autotaxin-IN-7 is a pyridine-2-carboxylic acid derivative with sub-nanomolar ATX inhibitory activity (IC50 = 0.086 nM), good cardiac safety (hERG > 30 μM), and extremely low fibroblast toxicity. | |
|
V118413 | BI-4659 | 894784-05-5 | BI-4659 (compound 47i) is a TGF-β type I receptor (TGF-βRI (Alk5)) inhibitor with an IC50 of 19 nM. |
|
V12686 | BIO-013077-01 | 746667-48-1 | BIO-013077-01 is a pyrazole-based TGF-β inhibitor. |
|
V131241 | CDD-1431 | 3034216-31-1 | CDD-1431 is a low nanomolar selective BMPR2 kinase inhibitor with a Kiapp value of 20.6 nM. |
|
V88160 | CDD-1653 | 3034216-44-6 | CDD-1653 is a potent and selective BMPR2 inhibitor (IC50=2.8 nM). |
|
V137413 | HM-279 | 3039954-64-5 | HM-279 is a potent and orally effective ALK5 inhibitor with an IC50 value of 4.7 nM. |
|
V137507 | HPH-15 | 1009838-93-0 | HPH-15 is an anti-migration compound that inhibits cell migration by binding to hnRNP U or by inhibiting the TGF-β signaling pathway. |
|
V67578 | KRFK | 162290-78-0 | KRFK is a bioactive peptide extracted from TSP-1 and can activate TGF-β. |
|
V3756 | LY3200882 | 1898283-02-7 | LY3200882 is a next generation,ATP competitive, potent, highly selective small molecule inhibitor of TGF-β receptor type 1 (TGFβRI). |
|
V78829 | MU1700 | MU1700 is an orally bioactive, potent ALK1/2 inhibitor (antagonist) with IC50s of 13 nM and 6 nM, respectively, which is cell membrane permeable (penetrable) and has high brain permeability. | |
|
V84564 | OXA-06 hydrochloride | 1825455-91-1 | |
|
V142786 | Pixofisiran sodium scrambled negative control | The Pixofisiran sodium scrambled negative control is a negative control with the sequence of Pixofisiran sodium scrambled. | |
|
V143802 | Ramatercept | 1169766-01-1 | Ramatercept is a soluble ActRIIB receptor antagonist that can be used as a soluble activin receptor 2 (ACVR2) antagonist. |
|
V144151 | Rinvatercept | 2996105-98-5 | Rinvatercept is a fusion protein consisting of glycyl chimeric N-terminal peptides (1-108) (2-109) spliced from human ACVR2A/B extracellular domain sequences, and fused to the Fc fragment of immunoglobulin G1 (IgG1) via the G3 peptide linker (110-112). |
|
V144214 | RKER-216 | RKER-216 is a human monoclonal IgG antibody inhibitor targeting ALK2 with a KD value of 58.7 pM. | |
|
V108648 | S58 aptamer | The S58 aptamer is a single-stranded DNA aptamer that targets transforming growth factor-β receptor II (TGF-β RII). |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
