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ADCs

ADCs

ADCs related products

Structure Cat No. Product Name CAS No. Product Description
ADC Control Human IgG1-sulfo-SPDB-DM4 V116955 ADC Control Human IgG1-sulfo-SPDB-DM4 ADC Control Human IgG1-sulfo-SPDB-DM4 is an antibody-drug conjugate (ADC) that inhibits microtubule polymerization.
Izeltabart (IMGC-936) V76158 Izeltabart (IMGC-936) 2642078-60-0 Izeltabart (IMGC-936) is a Maytansinoid-based ADC targeting ADAM9.
Mirzotamab clezutoclax V114499 Mirzotamab clezutoclax 2229859-12-3 Mirzotamab clezutoclax (ABBV-155) is a first-in-class antibody-drug conjugate (ADC) consisting of three components: an anti-B7-H3 monoclonal antibody and a BCL2L1 (BCL-XL) inhibitor, clezutoclaxum.
PF-08046054 V142520 PF-08046054 PF-08046054 is an antibody-drug conjugate (ADC) targeting PD-L1, which is composed of an anti-PD-L1 antibody conjugated with VcMMAE.
Sacituzumab tirumotecan V144495 Sacituzumab tirumotecan 2768350-77-0 Sacituzumab tirumotecan is an antibody-drug conjugate and a topoisomerase I inhibitor payload delivery agent targeting TROP2. Its TROP2 EC50 is 2.787 ng/ml, TROP2 Ka is 0.3083 nM, and topoisomerase I IC50 is 0.7 μmol/L.
Sirtratumab vedotin V144978 Sirtratumab vedotin 1824663-83-3 Sirtratumab vedotin is an antibody-drug conjugate (ADC) composed of a SLITRK6-specific human γ2 antibody (Igγ2) conjugated to a small microtubule disruptor, monomethylaurestatin E (MMAE), via a protease-cleavable linker.
Vandortuzumab vedotin V146854 Vandortuzumab vedotin 1471985-92-8 Vandortuzumab vedotin is an antibody-drug conjugate (ADC) that targets STEAP1.
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