| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V128053 | ABT-182 | ABT-182 is an antibody targeting human CCR8. | |
|
V3785 | BX-471 HCl | 288262-96-4 | BX471 HCl (also known as BX-471; ZK-811752) is a novel, oral and non-peptide antagonist of CCR1 (CC chemokine receptor-1)with potential anti-inflammatory activity. |
|
V3022 | BX471 | 217645-70-0 | BX471 (also known as ZK-811752) is a novel, oral and non-peptide antagonist of CCR1 (CC chemokine receptor-1) with Ki of 1 nM for human CCR1, and it may be useful in the treatment of chronic inflammatory diseases. |
|
V131206 | CCR2 antagonist 6 | 1421063-89-9 | CCR2 antagonist 6 is a CCR2 antagonist (CCR2 Kb value is 0.215 μM, hCCR2B Kb value is 0.174 μM). |
|
V84814 | CCR4 antagonist 4 | 668980-17-4 | |
|
V51092 | CCR6 inhibitor 1 | 2437547-04-9 | CCR6 Inhibitor 1 is a potent and potent example of CCR6 with IC50s of 0.45 and 6 nM for monkey and human CCR6, respectively, which is a close match for human CCR1 (IC50, >30000 nM) and CCR7 (IC50), 9400 nM). |
|
V3746 | Cenicriviroc | 497223-25-3 | Cenicriviroc (formerly known as TAK-652 or TBR-652) is a novel, orally bioactive, and dual antagonist of CCR2/CCR5, it also inhibits both HIV-1 and HIV-2, and has the potential for the treatment of HIV infection. |
|
V132581 | CXCR2/CCR7 antagonist-1 | 473728-04-0 | CXCR2/CCR7 antagonist-1 is a potent dual antagonist of CXCR2 and CCR7, with IC50 values of 0.0046 and 0.0014 μM, respectively. |
|
V106427 | Denrakibart | Denrakibart is an IgG2κ human antibody directed against CCL17. | |
|
V112090 | ECL1i | 1417312-35-6 | ECL1i is an allosteric selective CCR2 inhibitor. |
|
V108992 | ECL1i TFA | ECL1i TFA is an allosteric selective CCR2 inhibitor. | |
|
V4079 | INCB3344 | 1262238-11-8 | INCB3344 (INCB-3344) is a novel, potent, selective,orally bioavailable small molecule antagonist of the CCR2 receptor with anti-inflammatory activity. |
|
V106396 | Lanerkitug | Lanerkitug is a human IgG1λ2 antibody directed against CCR8. | |
|
V4298 | MK0812 | 624733-88-6 | MK-0812 (MK0812) is a novel, potent and selective small molecule CCR2 antagonist with potential anti-Inflammatory and immunomodulatory activity. |
|
V143276 | PROTAC CCR9 Degrader 1 | PROTAC CCR9 Degrader 1 is a PROTAC-based CCR9 degrader. | |
|
V14057 | RS-504393 | 300816-15-3 | RS-504393 is a potent and highly selective CCR2 chemokine receptor antagonist with IC50s of 98 nM and > 100 µM for inhibition of human recombinant CCR2b and CCR1 receptors respectively. |
|
V144479 | S-531011 | S-531011 is a human IgG1 monoclonal antibody (mAb) targeting CCR8. | |
|
V144480 | S-531011 (FUT8-KO) | S-531011 (FUT8-KO) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. | |
|
V3754 | SB297006 | 58816-69-6 | SB297006 (SB-297006) is an antagonist of CCR3 (Chemokine receptor, IC50 = 39 nM) with anticancer activity. |
|
V86575 | SQA1 | 1255915-27-5 | SQA1, a squaramide (SQA) derivative, is a CCR6 antagonist with a Kd of 250 nM. |
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