| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V2981 | AS1517499 | 919486-40-1 | AS1517499 is a potent STAT6 inhibitor with IC50of 21 nM. |
|
V2547 | BP-1-102 | 1334493-07-0 | BP-1-102 is a potent, orally bioavailable and selective STAT3 inhibitor, which binds Stat3 with an affinity Kd of 504 nM. |
|
V3113 | C188-9 | 432001-19-9 | C188-9 is a novel, potent and orally bioavailable STAT3 inhibitorthat binds to STAT3 with high affinity (KD=4.7±0.4 nM). |
|
V1384 | HO-3867 | 1172133-28-6 | HO-3867 (HO3867; HO 3867), an analog of curcumin, is a novel, selective and potent STAT3 inhibitor with potential antitumor activity. |
|
V142540 | P-gp-IN-36 | P-gp-IN-36 is a potent P-glycoprotein (P-gp) inhibitor with an EC50 value of approximately 1 μM. | |
|
V142866 | Plumericin | 77-16-7 | Plumericin is a drug with anti-inflammatory, antioxidant, and antibacterial properties. |
|
V143190 | pro-FTY | 3064707-13-4 | pro-FTY is an anticancer prodrug, FTY720, which belongs to the class of sphingosine-1-phosphate (S1P) inhibitors. |
|
V143283 | PROTAC c-Met degrader-5 | PROTAC c-Met degrader-5 is an orally effective c-Met PROTAC degrader with DC50 values of 0.42 nM and 0.32 nM in EBC-1 and Hs746T cells, respectively. | |
|
V143350 | PROTAC JAK2 degrader-1 | PROTAC JAK2 degrader-1 is a JAK2 PROTAC degrader with a half-lethal concentration (DC50) of 27.35 nM. | |
|
V143396 | PROTAC SKP2 Degrader-1 | 3120650-15-6 | PROTAC SKP2 Degrader-1 is a PROTAC degrader targeting SKP2 with a Kd value of 6.28 μM. |
|
V143402 | PROTAC STAT6 degrader-4 | 3103198-34-8 | PROTAC STAT6 degrader-4 is a STAT6 PROTAC degrader with a DC50 of 0.04 nM. |
|
V1378 | S3I-201 (NSC 74859) | 501919-59-1 | S3I-201 (also called S3I201;NSC74859;S3I 201;NSC-74859) is a cell permeable and selective Stat3 inhibitor with potential anticancer activity. |
|
V69140 | Salviolone | 119400-86-1 | Salviolone is a natural diterpene analogue that fights melanoma cells. |
|
V144662 | SBT-100 (His Tag) | SBT-100 (His Tag) is a human monoclonal antibody (mAb) that targets STAT3. | |
|
V144708 | SD-2301 | 3054116-24-1 | SD-2301 is a selective STAT3 PROTAC degrader. |
|
V144709 | SD-965 | 3054394-56-5 | SD-965 is a selective STAT3 PROTAC degrader with a DC50 of 0.14 μM. |
|
V1385 | SH-4-54 | 1456632-40-8 | SH-4-54 (SH 454;SH4-54; SH454;SH-454) is anovel and potent STAT inhibitor with potential antineoplastic activity. |
|
V144850 | SHP1 activator 1 | 3113070-25-7 | SHP1 activator 1 is an activator of Src homology domain 2 protein tyrosine phosphatase 1 (SHP1) with an EC50 value of 17.66 μM. |
|
V2551 | STA-21 | 111540-00-2 | STA-21(NSC628869; Ochromycinone; STA21; Rac-STA-21)is a potent STAT3 inhibitor and natural antibioticwith anticancer and antimicrobial activity. |
|
V145292 | STAT3-D11-PROTAC-VHL | STAT3-D11-PROTAC-VHL is a PROTAC degrader that targets signal transduction and transcription activator 3 (STAT3). |
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