| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V121811 | (E/Z)-Rilzabrutinib | 1575591-66-0 | (E/Z)-Rilzabrutinib is the cis-trans isomer of Rilzabrutinib. |
|
V87995 | (R)-NX-2127 | 3024312-52-2 | (R)-NX-2127 (compound 28) is an orally active Bruton's tyrosine kinase (Btk) degrader. |
|
V119798 | (Rac)-Ibrutinib alkyne | 936563-91-6 | (Rac)-ibrutinib alkyne (compound 8) is a Btk inhibitor with an IC50 of 0.72 nM. |
|
V0647 | (Z)-LFM-A13 | 244240-24-2 | (Z)-LFM-A13 (LFM-A1-3) is a novel, potent and specific Brutons tyrosine kinase (BTK) inhibitor with potential anticancer activity. |
|
V99657 | Btk substrate peptide | The Btk substrate peptide is a peptide substrate corresponding to residues 217-229 of human Bruton's tyrosine kinase (Btk), of which the tyrosine at residue 223 is the major autophosphorylation site of Btk. | |
|
V118856 | BTK V416L Recombinant Human Active Protein Kinase | Bruton's tyrosine kinase (BTK) plays a key role in the B cell antigen receptor (BCR) signaling pathway. | |
|
V130719 | BTK-IN-43 | 3081685-04-0 | BTK-IN-43 is a BTK inhibitor with an IC50 value of 21.6 nM. |
|
V116186 | BTK/IKZF1/3 ligand 1 | 1791402-90-8 | BTK/IKZF1/3 ligand 1 is a BTK/IKZF1/3 PROTAC ligand. |
|
V131432 | CFON-026 | 2941611-57-8 | CFON-026 is a selective, orally effective non-covalent BTK inhibitor with an IC50 value of 0.27 nM. |
|
V0646 | CGI1746 | 910232-84-7 | CGI1746 (CGI-1746) is a reversible/non-covalent and highly selective small-molecule inhibitor of the Brutons tyrosine kinase-Btk with potential anti-inflammatory activity. |
|
V0645 | CNX-774 | 1202759-32-7 | CNX-774 (CNX774) is an irreversible/covalent, orally bioavailable, and highly selective inhibitor of BTK (Brutons tyrosine kinase) with potential anticancer activity. |
|
V4775 | Nemtabrutinib (ARQ-531) | 2095393-15-8 | Nemtabrutinib (ARQ531; ARQ-531; MK-1026) is a novel, potent, orally bioavailable, and reversible / non-covalent BTK (Brutons Tyrosine Kinase) inhibitor with potential antitumor activity. |
|
V0649 | ONO-4059 analogue | 1351635-67-0 | ONO-4059 analogue, an analogue of ONO-4059, is a novel, covalent, selective and orally bioavailable BTK inhibitor with potential anticancer and anti-inflammatory activity. |
|
V116185 | PROTAC BTK/IKZF1/3 Degrader-1 | 2416130-49-7 | PROTAC BTK/IKZF1/3 Degrader-1 is a selective, orally effective BCL6 and IKZF1/3 PROTAC degrader. |
|
V87991 | QL47B TFA | QL47B TFA is a biotinylated analog of QL47 and is a potent BTK inhibitor with an IC50 of 1.3 μM. | |
|
V0648 | RN486 | 1242156-23-5 | RN486 (RN-486) is a novel, potent, reversible and selective BTK (Brutons tyrosine kinase) inhibitorwith potential anti-inflammatory activity. |
|
V145263 | SRX3305 | 2409965-28-0 | SRX3305 is a BTK/PI3K/BRD4 inhibitor with IC50 values of 6.5 nM, 15 nM, and 4 nM for BTK, PI3Kα, and PI3Kδ, respectively. |
|
V146173 | TLT8 | TLT8 is a ByeTAC protein degrader that targets BTK. | |
|
V146174 | TM471-1 | 2649008-95-5 | TM471-1 is an orally effective covalent Bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 1.3 nM (BTKWT), >40,000 nM (BTKC481S), 7.9 nM (TEC), and 12.4 nM (TXK). |
|
V0643 | Ibrutinib (PCI-32765) | 936563-96-1 | Ibrutinib(formerly PCI32765; trade name Imbruvica), an approved anticancer drug, is a covalent/irreversible and orally bioavailableBrutons tyrosine kinase (Btk) inhibitor with potential anti-cancer activity. |