| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V3102 | ASK1-IN-1 | 1262041-49-5 | ASK1-IN-1 is a potent inhibitor of the apoptosis signal regulating kinase 1 (ASK1) inhibitor (Compound 4 from patent WO2016025474A1). |
|
V74399 | TAK1-IN-2 | 2763213-98-3 | TAK1-IN-2 is a potent and specific TAK1 inhibitor (antagonist) with IC50> value of 2 nM. |
|
V145582 | TAO Kinase-IN-3 | 3114565-22-6 | TAO Kinase-IN-3 is a potent pan-TAOK (TAO-1 kinase) inhibitor that specifically binds to and inhibits the kinase activity of TAOK1, TAOK2, and TAOK3, with Kd values of <0.17 nM, 0.34 nM, and 0.17 nM, respectively. |
|
V147287 | ZAK-IN-1 | 2362525-64-0 | ZAK-IN-1 is an orally effective selective leucine zipper and sterile α-motif kinase (ZAK) inhibitor with an IC50 of 4 nM and a KD of 8 nM. |
|
V2973 | Selonsertib | 1448428-04-3 | Selonsertib (Also known as GS-4997) is a highly selective and potent once-daily orally available inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with a pIC50 of 8.3±0.07. |
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