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c-Kit

c-Kit

c-Kit related products

Structure Cat No. Product Name CAS No. Product Description
(S)-c-Kit-IN-12 V109189 (S)-c-Kit-IN-12 2797973-69-2 (S)-c-Kit-IN-12 (compound 2b) is a potent c-Kit inhibitor with IC50 values of less than 10 nM against c-Kit in four KIT mutant cell models (BAF3 KIT EX11 DEL, EX11 DEL/D816H, EX11 DEL/T670I, and EX11 DEL/V654A).
AZD3229 V3474 AZD3229 2248003-60-1 AZD3229 (AZD-3229) is a novel, potent, pan-KIT mutantinhibitor with anticancer activity.
c-Kit-IN-10 V120281 c-Kit-IN-10 1123512-36-6 c-Kit-IN-10 (compound 1) is a c-Kit inhibitor.
c-Kit-IN-15 V131853 c-Kit-IN-15 c-Kit-IN-15 is a c-Kit inhibitor.
DCC-2618 HCl V3757 DCC-2618 HCl Ripretinib HCl (DCC2618; DCC-2618; Qinlock), the hydrochloride salt of DCC-2618, is an orally bioactive pan KIT and PDGFRA inhibitor approved in 2020 for the treatment of adults with advanced gastrointestinal stromal tumor.
EGFR-IN-164 V134970 EGFR-IN-164 EGFR-IN-164 is a selective covalent allosteric EGFR inhibitor.
KIT V559D/T670I Recombinant Human Active Protein Kinase V118895 KIT V559D/T670I Recombinant Human Active Protein Kinase KIT (CD117) is an important cell surface marker used to identify certain types of hematopoietic progenitor cells in the bone marrow.
Opelkibart V141929 Opelkibart 2771389-44-5 Opelkibart is a monoclonal antibody against KIT human IgG1κ.
SU14813 V15392 SU14813 627908-92-3 SU14813 is a novel, orally bioavailable, multi-targeted tyrosine kinase inhibitor (TKI) withIC50s of 50, 2, 4, 15 nM forVEGFR2,VEGFR1,PDGFRβandKIT, respectively.
VEGFR2-IN-84 V146921 VEGFR2-IN-84 861877-12-5 VEGFR2-IN-84 is an orally active multi-target tyrosine kinase inhibitor based on a naphthalene ring skeleton.
培西达替尼 V0630 Pexidartinib (PLX3397; Turalio; CML261; FP113) 1029044-16-3 Pexidartinib (formerly PLX-3397; CML-261;FP-113; trade name Turalio) is an orally bioavailable and multi-targeted RTK (receptor tyrosine kinase) inhibitor of CSF-1R, Kit, and Flt3 with potential antineoplastic activity.
甲磺酸伊马替尼 V0572 Imatinib Mesylate (STI571; Gleevec; Glivec) 220127-57-1 Imatinib Mesylate (also known as STI571 mesylate; trade names: Gleevec or Glivec), the mesylate salt of imatinib, is an orally bioavailable,potent,multi-kinase inhibitor of v-Abl, c-Kit and PDGFR with potential antitumor activity.
达沙替尼一水合物 V0631 Dasatinib Monohydrate (BMS354825; Sprycel) 863127-77-9 Dasatinib (formerly BMS-354825; trade name Sprycel), an approved anticancer drug, is an orally bioavailable and multi-targeted kinase inhibitorof Abl, Src and c-Kit with potential anticancer activity.
阿伐普替尼 V2886 Avapritinib 1703793-34-3 Avapritinib (formerly known as BLU-285; trade name Ayvakit) is an oral, potent and selective small molecule inhibitor of PDGFRα D842V and KIT Exon 17 mutants (IC50=0.5 nM) with anticancer activity.
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