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TRP Channel

TRP Channel

TRP Channel related products

Structure Cat No. Product Name CAS No. Product Description
2-(1,3-二甲基-2,6-二氧代-2,3-二氢-1H-嘌呤-7(6H)-基)-N-(4-异丙基苯基)乙酰胺 V0023 HC-030031 (TOSLAB-829227) 349085-38-7 HC-030031 (also known as TOSLAB 829227)is a novel, potent and selective blocker/antagonist/inhibitor of TRPA1 (transient receptor potential ankyrin 1) channel.
2-(2-Methylbenzamido)acetic acid-d7 (2-methylhippuric acid d7) V81847 2-(2-Methylbenzamido)acetic acid-d7 (2-methylhippuric acid d7) 1216430-90-8 2-(2-Methylbenzamido)acetic acid-d7 is the deuterium labelled form of 2-(2-Methylbenzamido)acetic acid.
3,3-Azo-1-butanol V125046 3,3-Azo-1-butanol 25055-82-7 3,3-Azo-1-butanol is an orally effective hypoglycemic agent.
5-Iodoresiniferatoxin (I-RTX) V70162 5-Iodoresiniferatoxin (I-RTX) 535974-91-5 5-Iodoresiniferatoxin (I-RTX) is a selective TRPV1 antagonist (inhibitor) with IC50 of 0.7 and 5.4 nM for rat and human receptors, respectively.
8-Br-ADPR disodium V127753 8-Br-ADPR disodium 8-Br-ADPR disodium is a TRPM2 inhibitor and ADPR signaling pathway antagonist.
A-967079 V6545 A-967079 1170613-55-4 A-967079 is a novel, potent, CNS-penetrant and selective blocker/antagonist TRPA1 channel (IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors), with analgesic and antiinflammatory effects and is used in scientific research, but has not been developed for medical use.
AM-0902 V6706 AM-0902 1883711-97-4 AM-0902 is a novel, potent and selective Transient Receptor Potential A1 (TRPA1) antagonist withIC50s of 71 and 131 nM forrTRPA1andhTRPA1, respectively.
CEDAEVFKDSMVPGEK V78708 CEDAEVFKDSMVPGEK CEDAEVFKDSMVPGEK is a rat capsaicin receptor subtype 1 (VR1) peptide sequence fragment that may be utilized to detect the presence, distribution and molecular morphology of VR1.
GSK3527497 V136963 GSK3527497 2215855-22-2 GSK3527497 is an orally effective TRPV4 inhibitor.
HZS60 V137733 HZS60 3027529-88-7 HZS60 is a brain-penetrating NMDAR/TRPM4 inhibitor that can improve cerebral ischemia.
Icilin V2999 Icilin 36945-98-9 Icilin (also known as AG-3-5 or AG 3-5) is a synthetic CMR1/TRPM8 (transient receptor potential M8) super-cooling agent/agonist that is 2.5-fold more efficacious and nearly 200-fold more potent than the reference cold thermosensory agonist, l-menthol.
OptoBI-1 V70134 OptoBI-1 2415272-11-4 OptoBI-1 is a photochromic TRPC3 agonist that may serve as a photopharmacological tool to control neuronal firing.
Optovin V1910 Optovin 348575-88-2 Optovin is a potent and reversible photoactivated TRPA1 activator that is able to activate human TRPA1 via structure dependent photochemical reactions.
PF-4840154 V4431 PF-4840154 1332708-14-1 PF-4840154 is a novel, potent, selective agonist of the rat and humanTrpA1channel withEC50s of 97 and 23 nM, respectively.
Phenamil methanesulfonate V73672 Phenamil methanesulfonate 1161-94-0 Phenamil methanesulfonate is an analogue of Amiloride, a more potent and irreversible epithelial sodium channel (ENaC) blocker with IC50 of 400 nM.
Ponometrep V143033 Ponometrep 2776175-74-5 Ponometrep is a transient receptor potential melastatin 3 (TRPM3) antagonist with an IC50 value of 1-10 nM.
Pregnenolone-d6 V109734 Pregnenolone-d6 Pregnenolone-d6 (3β-hydroxy-5-pregnen-20-one-d6) is a deuterated derivative of pregnenolone.
Ricorfotide vedotin V144130 Ricorfotide vedotin 2082631-84-1 Ricorfotide vedotin is a dual-ligand peptide-drug conjugate (PDC) that is conjugated to MMAE and targets folate receptor α (FRα) and TRPV6.
SB-366791 V2819 SB-366791 472981-92-3 SB-366791 is a competitive and selective cinnamide TRPV1 (Vanilloid receptor 1) antagonist identified via high-throughput screening of a large chemical library.
T100-Mut V145502 T100-Mut T100-Mut is a cell-permeable peptide whose N-terminus is coupled with a myristyl group, enabling T100-Mut to penetrate and localize to the inner side of the plasma membrane, thereby mimicking the topological structure of Tmem100-3Q.
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