| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V96811 | Antiproliferative agent-57 | Antiproliferative agent-57 (Compound M2) is a tumor angiogenesis inhibitor. | |
|
V110850 | DS79540454 | 1462947-17-6 | DS79540454 is a HIF-PHD2 inhibitor with an IC50 of 0.26 μM. |
|
V110785 | eIF3e-IN-1 | eIF3e-IN-1 (compound 209) is an eIF3e inhibitor with an EC50 value of 18.3 μM. | |
|
V78503 | HIF-1 inhibitor-5 | HIF-1 inhibitor-5 (Compound 16e) is a potent HIF-1 inhibitor (antagonist) with IC50 of 2.38 μM. | |
|
V119403 | HIF-1α-IN-8 | HIF-1α-IN-8 is an orally effective HIF-1α inhibitor with an IC50 value of 2.02 μM. | |
|
V51618 | HIF-2α agonist 2 | 2750141-15-0 | HIF-2α Agonist 2 (Compound 10) is a HIF-2α agonist/activator with EC50 of 1.68 μM at a dose of 20 μM. |
|
V73838 | HIF-2α-IN-9 | 2648334-36-3 | HIF-2α-IN-9 (compound 35r) is an inhibitor (blocker/antagonist) of HIF-2α. |
|
V2781 | LW6 | 934593-90-5 | LW6 is a hypoxia-inducible factor 1 (HIF) inhibitor which potently inhibits HIF-1α accumulation by degrading HIF-1α without affecting the HIF-1a mRNA levels during hypoxia. |
|
V120114 | PHD2-IN-6 | 1193382-79-4 | PHD2-IN-6 (Example 89) is a HIF prolyl hydroxylase 2 (PHD2) inhibitor with an IC50 of 31.6 nM. |
|
V104413 | PROTAC HIF-1α degrader-1 | PROTAC HIF-1α Degrader-1 (Compound V2) is a potent hypoxia-inducible factor-1α (HIF-1α) PROTAC degrader with an IC50 value of 7.54 µM. | |
|
V4090 | PT-2385 | 1672665-49-4 | PT2385 (PT-2385) is a nove, potent, selective and orally bioactive inhibitor of hypoxia inducible factor (HIF-2α) with anticancer and anti-hepatic steatosis activity. |
|
V51630 | Dimethyl-bisphenol A | 1568-83-8 | Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. |
|
V0252 | Hydralazine HCl (Apresoline, Adrolazine , Apresrex) | 304-20-1 | Hydralazine HCl (Apresoline, Adrolazine , Apresrex), thehydrochloride salt of hydralazine,is a potent and direct-acting smooth muscle relaxant and vasodilatorused for the treatment of hypertension. |
|
V2958 | Molidustat | 1154028-82-6 | Molidustat (formerly known as BAY 85-3934) is a novel potent inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. |
|
V2834 | Daprodustat (GSK1278863) | 960539-70-2 | Daprodustat (formerly known as GSK1278863; Duvroq) is a novel orally bioavailable hypoxia-inducible factor prolyl hydroxylase (HIF-PHI)inhibitor that has been approved for treatment of anemia associated with CKD/chronic kidney disease. |