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HIF HIF Prolyl-Hydroxylase

HIF HIF Prolyl-Hydroxylase

HIF HIF Prolyl-Hydroxylase related products

Structure Cat No. Product Name CAS No. Product Description
Antiproliferative agent-57 V96811 Antiproliferative agent-57 Antiproliferative agent-57 (Compound M2) is a tumor angiogenesis inhibitor.
DS79540454 V110850 DS79540454 1462947-17-6 DS79540454 is a HIF-PHD2 inhibitor with an IC50 of 0.26 μM.
eIF3e-IN-1 V110785 eIF3e-IN-1 eIF3e-IN-1 (compound 209) is an eIF3e inhibitor with an EC50 value of 18.3 μM.
HIF-1 inhibitor-5 V78503 HIF-1 inhibitor-5 HIF-1 inhibitor-5 (Compound 16e) is a potent HIF-1 inhibitor (antagonist) with IC50 of 2.38 μM.
HIF-1α-IN-8 V119403 HIF-1α-IN-8 HIF-1α-IN-8 is an orally effective HIF-1α inhibitor with an IC50 value of 2.02 μM.
HIF-2α agonist 2 V51618 HIF-2α agonist 2 2750141-15-0 HIF-2α Agonist 2 (Compound 10) is a HIF-2α agonist/activator with EC50 of 1.68 μM at a dose of 20 μM.
HIF-2α-IN-9 V73838 HIF-2α-IN-9 2648334-36-3 HIF-2α-IN-9 (compound 35r) is an inhibitor (blocker/antagonist) of HIF-2α.
LW6 V2781 LW6 934593-90-5 LW6 is a hypoxia-inducible factor 1 (HIF) inhibitor which potently inhibits HIF-1α accumulation by degrading HIF-1α without affecting the HIF-1a mRNA levels during hypoxia.
PHD2-IN-6 V120114 PHD2-IN-6 1193382-79-4 PHD2-IN-6 (Example 89) is a HIF prolyl hydroxylase 2 (PHD2) inhibitor with an IC50 of 31.6 nM.
PROTAC HIF-1α degrader-1 V104413 PROTAC HIF-1α degrader-1 PROTAC HIF-1α Degrader-1 (Compound V2) is a potent hypoxia-inducible factor-1α (HIF-1α) PROTAC degrader with an IC50 value of 7.54 µM.
PT-2385 V4090 PT-2385 1672665-49-4 PT2385 (PT-2385) is a nove, potent, selective and orally bioactive inhibitor of hypoxia inducible factor (HIF-2α) with anticancer and anti-hepatic steatosis activity.
双酚A二甲醚 V51630 Dimethyl-bisphenol A 1568-83-8 Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor.
盐酸肼屈嗪 V0252 Hydralazine HCl (Apresoline, Adrolazine , Apresrex) 304-20-1 Hydralazine HCl (Apresoline, Adrolazine , Apresrex), thehydrochloride salt of hydralazine,is a potent and direct-acting smooth muscle relaxant and vasodilatorused for the treatment of hypertension.
莫度司他 V2958 Molidustat 1154028-82-6 Molidustat (formerly known as BAY 85-3934) is a novel potent inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells.
达普司他 V2834 Daprodustat (GSK1278863) 960539-70-2 Daprodustat (formerly known as GSK1278863; Duvroq) is a novel orally bioavailable hypoxia-inducible factor prolyl hydroxylase (HIF-PHI)inhibitor that has been approved for treatment of anemia associated with CKD/chronic kidney disease.
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