| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V70111 | Acoramidis hydrochloride (AG10 hydrochloride) | 2242751-53-5 | Acoramidis (AG10) HCl is an orally bioactive, selective stabilizer of transthyretin (TTR (transthyretin)), effective against both wild-type and V1221 mutants. |
|
V70110 | Inotersen sodium (ISIS-420915 sodium) | 1432726-13-0 | Inotersen (ISIS-420915) sodium is a 2'-O-methoxyethyl modified antisense oligonucleotide. |
|
V70106 | Patisiran sodium | 1386913-72-9 | Patisiran sodium is a double-stranded small interfering RNA that targets sequences within the Transthyretin (TTR) messenger RNA. |
|
V146376 | Transthyretin-IN-4 | 2765296-93-1 | Transthyretin-IN-4 is a bivalent inhibitor of transthyretin (TTR) amyloidosis (bIC50: 0.09 µM, pIC50: 1.4 µM). |
|
V97925 | TTR stabilizer 1 | 2778162-15-3 | TTR stabilizer 1 (Compound 1) is a stabilizer of transthyretin (TTR) with an EC50 value of 0.031 μM. |
|
V14470 | Tafamidis meglumine (Fx1006, PF06291826) | 951395-08-7 | Tafamidismeglumine(formerly Fx-1006; PF-06291826; Vyndaqel and Vyndamax), the meglumine salt of tafamidis, is a potent and selective transthyretin (TTR)stabilizer, is an approved drug for the amelioration of transthyretin-related hereditary amyloidosis (also familial amyloid polyneuropathy, or FAP), a rare but deadly neurodegenerative disease. |