| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V107660 | 21-Hydroxyeplerenone | 334678-67-0 | 21-Hydroxyeplerenone is the major metabolite of the mineralocorticoid receptor antagonist eplerenone, which is formed from eplerenone via the cytochrome P450 (CYP) isozyme CYP3A4. |
|
V87597 | Vicadrostat | 1868065-21-7 | Vicadrostat is an aldosterone synthase inhibitor (IC50=48 nM). |
|
V2139 | Eplerenone (Epoxymexrenone; CGP 30083) | 107724-20-9 | Eplerenone (also known as CGP 30083, Inspra,SC-66110) is a potent and selective mineralocorticoid receptor antagonist with an IC50 of 0.36 μM, it blocks the action of aldosterone, used to control high blood pressure. |
|
V20709 | Esaxerenone | 1632006-28-0 | Esaxerenone, formerly known as CS-3150, XL-550, is a nonsteroidal antimineralocorticoid which was discovered by Exelixis and is now under development by Daiichi Sankyo Company for the treatment of hypertension, essential hypertension, hyperaldosteronism, and diabetic nephropathies. |