| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V88082 | BPR5K230 | 3029897-97-7 | BPR5K230 is a dual inhibitor of receptor tyrosine kinases MER and AXL with IC50 of 4.1 nM and 9.2 nM, respectively. |
|
V0638 | LDC1267 | 1361030-48-9 | LDC1267 (LDC-1267) is a novel, highly potent and selective TAM (Tyro3, Axl and Mer) kinase inhibitor with potential antitumor activity. |
|
V0595 | NPS-1034 | 1221713-92-3 | NPS-1034 (NPS1034; NPS 1034) is a novel, potent dual inhibitor of the tyrosine kinases Met and Axl with potential antineoplastic activity. |
|
V120353 | SLC-391 | 1783825-18-2 | SLC-391 is a selective, orally effective AXL inhibitor with an IC50 of 9.6 nM. |
|
V0636 | UNC2250 | 1493694-70-4 | UNC2250 (UNC-2250) is a novel, potent and selective Mer inhibitor with potential antitumor activity. |
|
V0637 | UNC2881 | 1493764-08-1 | UNC2881 (UNC-2881) is a novel, potent and specific Mer tyrosine kinase inhibitor with potential utility for prevention and treatment of pathologic thrombosis. |
|
V69566 | UNC1062 | 1350549-36-8 | UNC1062 is a MERTK-selective tyrosine kinase inhibitor that reduces the activation of MERTK-mediated downstream signaling, causes apoptosis in culture, reduces colony formation in soft agar, and inhibits melanoma cell invasion. |
|
V146764 | UNC8212 | UNC8212 is a TAM kinase inhibitor. | |
|
V146766 | UNC9426 | 3051784-94-9 | UNC9426 is a highly effective and selective TYRO3 inhibitor (IC50 = 2.1 nM), with selectivity for MERTK and AXL that is 276-fold and 90-fold higher, respectively. |
|
V146767 | UNC9435 | 3091640-25-1 | UNC9435 is a dual inhibitor of TYRO3/MERTK, with IC50 values of 3.7 nM and 1.1 nM, respectively. |
|
V0639 | Dubermatinib (TP-0903) | 1341200-45-0 | Dubermatinib (formerly also known as TP-0903;TP-0903) is a novel, selective and orally bioavailable inhibitor of the AXL receptor tyrosine kinase with potential antineoplastic activity. |
|
V0635 | Bemcentinib (R428; BGB-324; R-428) | 1037624-75-1 | Bemcentinib (formerly known as BGB324; R428) is a novel, potent and selectiveinhibitor of the RTK (receptor tyrosine kinase) Axl with potential anticancer activity. |
|
V33826 | Glesatinib hydrochloride | 1123838-51-6 | Glesatinib HCl (MGCD265 HCl) is an orally bioactive, potent dual MET/SMO inhibitor. |
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