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Complement System

Complement System

Complement System related products

Structure Cat No. Product Name CAS No. Product Description
ARC186 sodium V86833 ARC186 sodium ARC186 (sodium) is a PEGylated nucleic acid aptamer.
Avacincaptad pegol V74790 Avacincaptad pegol 1613641-69-2 Avacincaptad pegol (Izervay) is a nucleic acid aptamer that works as a C5 complement inhibitor to reduce inflammation-related retinal pigment epithelial (RPE) damage.
Bisphenol A bissulfate disodium V119513 Bisphenol A bissulfate disodium 10040-44-5 Sodium bisulfate of bisphenol A is a metabolite of bisphenol A.
BuChE-IN-23 V130739 BuChE-IN-23 3067571-93-8 BuChE-IN-23 is an orally effective, blood-brain barrier-crossing butyrylcholinesterase (eqBuChE) inhibitor with an IC50 of 15.59 μM and a Ki of 29.33 μM.
C1s-IN-1 trihydrochloride V130873 C1s-IN-1 trihydrochloride 1376162-36-5 C1s-IN-1 trihydrochloride is a selective inhibitor of C1s protease with a Ki value of 5.8 μM.
C5aR1 antagonist 1 V86829 C5aR1 antagonist 1 2365325-67-1 C5aR1 antagonist 1 (compound 7e) is an orally available C5aR antagonist.
Cemdisiran sodium scrambled negative control V131368 Cemdisiran sodium scrambled negative control The scrambled negative control is a negative control for Cemdisiran sodium with its sequence scrambled.
Cevolisiran sodium scrambled negative control V131428 Cevolisiran sodium scrambled negative control Cevolisiran sodium scrambled negative control is a negative control with the sequence of Cevolisiran sodium scrambled.
Complement factor D-IN-2 V3627 Complement factor D-IN-2 1903742-34-6 Complement factor D-IN-2 (extracted fromWO2015130838A1, compound 190) is an inhibitor of complement factor D with the potential to be used for treating autoimmune diseases.
MK-4721 V140031 MK-4721 MK-4721 is a fully human IgG1κ monoclonal antibody targeting PSCA with a Ka value of 0.2 nM.
Omoprubart V141898 Omoprubart 2763342-87-4 Omoprubart is a recombinant humanized monoclonal antibody against C5 complement.
PMX 205 Trifluoroacetate V76618 PMX 205 Trifluoroacetate PMX 205 Trifluoroacetate is a potent complement C5a receptor (C5aR; CD88) antagonist.
Riliprubart (SAR 445088) V74797 Riliprubart (SAR 445088) 2756228-76-7 Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody (mAb) that can inhibit activated C1s in the proximal part of the classical complement system.
RPARPAR V144383 RPARPAR 1184942-81-1 RPARPAR is a CendR tumor-penetrating peptide.
RPARPAR acetate V144384 RPARPAR acetate RPARPAR acetate is a CendR tumor-penetrating peptide.
Ruxoprubart V144427 Ruxoprubart 2842046-67-5 Ruxoprubart is a complement factor B (Bb subunit) inhibitor.
Sefaxersen sodium V144746 Sefaxersen sodium 2272983-11-4 Sefaxersen sodium is a specific antisense oligonucleotide (ASO) that targets complement factor B (CFB).
Tanruprubart V145579 Tanruprubart 2065212-40-8 Tanruprubart is a C1q inhibitor and C1q depletor.
Tarvicopan V145591 Tarvicopan 2378381-06-5 Tarvicopan is an inhibitor of complement factor D.
TAT-327 V145597 TAT-327 TAT-327 is a cell-penetrating peptide.
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