Histone Demethylase

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Histone Demethylase

Histone Demethylase related products

Cat No.	Product Name	CAS No.	Product Description
V56074	(1R,2S)-NCD38 TFA	2078047-42-2	(1R,2S)-NCD38 TFA is an enantiomer of NCD38 TFA.
V0372	IOX1	5852-78-8	IOX1 (5-Carboxy-8-hydroxyquinoline) is a novel, potent and broad-spectrum inhibitor of 2OG oxygenases (e.
V94227	Acaricide		The acaricide (compound 7l) is a potent LSD1 inhibitor.
V128069	Acaricide agent 1		Acaricide agent 1 is a potent LSD1 inhibitor.
V2982	AS8351	796-42-9	AS8351 is a potent inhibitor of KDM5B (lysine-specific histone demethylase 5B) which plays an important role in maintaining cancer stem cells and justifies the rationale for studying the effects of continuous inhibition of this epigenetic factor in cancer.
V56067	CBB1007 hydrochloride	2070014-96-7	CBB1007 HCl is a highly efficient substrate competitive, reversible, and selective inhibitor of the histone demethylase LSD1, with IC50 of 5.27 uM for hLSD1.
V2606	CPI-455	1628208-23-0	CPI-455 is a novel, potent andspecific inhibitor of the KDM5demethylase which catalyzes the demethylation of histone H3 on lysine 4 (H3K4) and is required for the survival of drug-tolerant persister cancer cells (DTPs).
V2936	DDP-38003 dihydrochloride	1831167-98-6	DDP-38003 dihydrochloride, atranylcypromine (TCPA) derivative, is a novel, potent and orally bioavailable inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1).
V77096	DDP-38003 trihydrochloride		DDP-38003 triHCl is a novel, orally bioactive KDM1A/LSD1 inhibitor (antagonist) with IC50 of 84 nM.
V52030	GSK 690 Hydrochloride	2436760-79-9	GSK 690 ( HCl) is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) with a Kd of 9 nM and IC50 of 37 nM.
V4761	GSK J4 HCl	1797983-09-5	GSK J4 (GSK-J4) is a novel,cell permeable, and potent prodrug of GSK J1 with anti-inflammatory effects.
V45816	GSK-690 HCl		GSK-690 hydrochloride is a selective reversible inhibitor of lysine specific demethylase 1(LSD1) with anticancer activity.
V2660	GSK-J4	1373423-53-0	GSK J4 is a novel,cell permeable, and potent prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase (KDM) JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and is inactive against a panel of demethylases of the JMJ family.
V52029	GSK-LSD1 dihydrochloride	2102933-95-7	GSK-LSD1 diHCl is a potent, selective, irreversible inhibitor of lysine-specific demethylase (LSD1) with IC50 of 16 nM.
V4128	GSK2807 TFA	2245255-66-5	GSK2807 TFA (GSK-2807 TFA), the trifluoroacetic acid salt form ofGSK2807, is a selective and SAM-competitiveSMYD3inhibitorwith potential antitumor activity.
V0371	JIB-04 (NSC-693627)	199596-05-9	JIB-04 (also known as NSC693627) is anovel, potent and pan-selective inhibitor of Jumonji histone demethylase (JMJD) inhibitor with antineoplastic activity.
V51918	JNJ-9350	326923-09-5	JNJ-9350 is an inhibitor (blocker/antagonist) of spermine oxidase (SMOX) with IC50 of 0.01 μM.
V80481	KDOAM-25 trihydrochloride		KDOAM-25 tri HCl is a potent and selective inhibitor of histone lysine demethylase 5 (KDM5), with IC50s of 71 nM, 19 nM, 69 nM, and 69 nM for KDM5A, KDM5B, KDM5C, and KDM5D respectively.
V85462	LSD1-IN-30	1289575-45-6
V139086	LSD1-IN-43		LSD1-IN-43 is a highly selective, reversible, orally effective LSD1 inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.8 μM.