| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V51337 | 10-Nitrolinoleic acid | 774603-04-2 | 10-Nitrolinoleic acid is a novel agonist for the peroxisome proliferator-activated receptor γ (PPARγ). |
|
V52518 | 23-epi-26-Deoxyactein (27-Deoxyactein) | 501938-01-8 | 23-epi-26-Deoxyactein is a natural, orally biologically active compound with anti-obesity and anti-tumor effects. |
|
V128672 | Amezalpat | 1616372-41-8 | Amezalpat is a PPARα antagonist with an IC50 of 58 nM. |
|
V96897 | AMG131 benzenesulfonate | 849738-78-9 | AMG131 (INT131) (benzenesulfonate) is a potent non-thiazolidinone (TZD) selective peroxisome proliferator-activated receptor gamma modulator (SPPARM). |
|
V105429 | Anti-NASH agent 2 | 3028778-28-8 | Anti-NASH agent 2 (compound 21) is an anti-de novo lipogenic activity and α-SMA gene expression inhibitor. |
|
V2840 | BMS-687453 | 1000998-59-3 | BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with anEC50andIC50of 10 nM and 260 nM for humanPPARαand 4100 nM and >15000 nM for PPARγ in PPAR-GAL4 transactivation assays. |
|
V3800 | BMS-711939 | 1000998-62-8 | BMS-711939, an analog of BMS-687453, is a novel potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC50 and IC50 of 4 nM for human PPARα and >1000-fold selectivity vs human PPARγ (EC50 of 4.5 μM) and PPARδ (EC50 > 100 μM) in PPAR-GAL4 transactivation assays. |
|
V115240 | BR101549 | 2252478-54-7 | BR101549 is a non-thiazolidinedione peroxisome proliferator-activated receptor γ (PPARγ) agonist. |
|
V54370 | CRX000227 | 686769-92-6 | CRX000227 is a PPAR modulator. |
|
V3186 | Elafibranor | 923978-27-2 | Elafibranor (formerly GFT505) is a dual agonist of the PPARα/δ (peroxisome proliferator-activated receptor-α and -δ) with EC50 values of 45 and 175 nM, respectively. |
|
V32180 | Etrinabdione (EHP-101; VCE-004.8) | 1818428-24-8 | VCE-004.8, a semi-synthetic multitarget cannabinoquinoid, is a specific PPARγ and CB2 receptor dual agonist with potent anti-inflammatory activity. |
|
V0831 | FH535 | 108409-83-2 | FH535 (FH-535; FH 535) is a novel and potent dual inhibitor of the Wnt/β-catenin and the PPAR (γ/δ) pathways with potential antitumor activity. |
|
V3035 | GSK0660 | 1014691-61-2 | GSK0660 is a potent and selective antagonist of PPARβ and PPARδ with IC50values of both 155 nM, it has little or no activity on PPARα and PPARγ with IC50values of >10 μM. |
|
V0830 | GSK3787 | 188591-46-0 | GSK3787 (GSK-3787; GSK 3787) isa novel, potent, selective and irreversible antagonist of PPARδ (Peroxisome proliferator-activated receptor δ) with important biological activity. |
|
V0832 | GW0742 | 317318-84-6 | GW0742 (GW-0742; GW 0742; GW-0742X; GW0742X; GW610742; GW-610742) is a potent and highly selective PPARβ/δ agonist with potential anti-inflammatory activity. |
|
V0826 | GW9662 | 22978-25-2 | GW9662 (GW-9662; GW 9662) is an irreversible and selective inhibitor of PPAR (peroxisome proliferator-activated receptor) with potential anticancer activity. |
|
V5144 | Indeglitazar (PPM 204 and PLX 204) | 835619-41-5 | Indeglitazar (formerly PPM-204 and PLX-204) is a novel, potent and orally bioavailable peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). |
|
V88747 | Methyl clofenapate | 21340-68-1 | Methyl clofenapate (Clofenapate methyl ester; MCP) is a peroxisome proliferator that can induce hypolipidemia, peroxisome proliferation, and hepatocarcinogenesis. |
|
V51327 | PPARα/γ agonist 2 | 2213365-56-9 | PPARα/γ agonist 2 is a novel and potent PPARα full agonist and PPARγ partial agonist. |
|
V101074 | PPARα/γ agonist 4 | PPARα/γ agonist 4 (Compound (S)-7) is an orally available dual potent activator of PPARα and PPARγ with EC50 values of 0.061 μM and 1.42 μM, respectively. |