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PPAR

PPAR

PPAR related products

Structure Cat No. Product Name CAS No. Product Description
10-硝基亚油酸 V51337 10-Nitrolinoleic acid 774603-04-2 10-Nitrolinoleic acid is a novel agonist for the peroxisome proliferator-activated receptor γ (PPARγ).
23-epi-26-Deoxyactein (27-Deoxyactein) V52518 23-epi-26-Deoxyactein (27-Deoxyactein) 501938-01-8 23-epi-26-Deoxyactein is a natural, orally biologically active compound with anti-obesity and anti-tumor effects.
Amezalpat V128672 Amezalpat 1616372-41-8 Amezalpat is a PPARα antagonist with an IC50 of 58 nM.
AMG131 benzenesulfonate V96897 AMG131 benzenesulfonate 849738-78-9 AMG131 (INT131) (benzenesulfonate) is a potent non-thiazolidinone (TZD) selective peroxisome proliferator-activated receptor gamma modulator (SPPARM).
Anti-NASH agent 2 V105429 Anti-NASH agent 2 3028778-28-8 Anti-NASH agent 2 (compound 21) is an anti-de novo lipogenic activity and α-SMA gene expression inhibitor.
BMS-687453 V2840 BMS-687453 1000998-59-3 BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with anEC50andIC50of 10 nM and 260 nM for humanPPARαand 4100 nM and >15000 nM for PPARγ in PPAR-GAL4 transactivation assays.
BMS-711939 V3800 BMS-711939 1000998-62-8 BMS-711939, an analog of BMS-687453, is a novel potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC50 and IC50 of 4 nM for human PPARα and >1000-fold selectivity vs human PPARγ (EC50 of 4.5 μM) and PPARδ (EC50 > 100 μM) in PPAR-GAL4 transactivation assays.
BR101549 V115240 BR101549 2252478-54-7 BR101549 is a non-thiazolidinedione peroxisome proliferator-activated receptor γ (PPARγ) agonist.
CRX000227 V54370 CRX000227 686769-92-6 CRX000227 is a PPAR modulator.
Elafibranor V3186 Elafibranor 923978-27-2 Elafibranor (formerly GFT505) is a dual agonist of the PPARα/δ (peroxisome proliferator-activated receptor-α and -δ) with EC50 values of 45 and 175 nM, respectively.
Etrinabdione (EHP101; VCE004.8) V32180 Etrinabdione (EHP-101; VCE-004.8) 1818428-24-8 VCE-004.8, a semi-synthetic multitarget cannabinoquinoid, is a specific PPARγ and CB2 receptor dual agonist with potent anti-inflammatory activity.
FH535 V0831 FH535 108409-83-2 FH535 (FH-535; FH 535) is a novel and potent dual inhibitor of the Wnt/β-catenin and the PPAR (γ/δ) pathways with potential antitumor activity.
GSK0660 V3035 GSK0660 1014691-61-2 GSK0660 is a potent and selective antagonist of PPARβ and PPARδ with IC50values of both 155 nM, it has little or no activity on PPARα and PPARγ with IC50values of >10 μM.
GSK3787 V0830 GSK3787 188591-46-0 GSK3787 (GSK-3787; GSK 3787) isa novel, potent, selective and irreversible antagonist of PPARδ (Peroxisome proliferator-activated receptor δ) with important biological activity.
GW0742 V0832 GW0742 317318-84-6 GW0742 (GW-0742; GW 0742; GW-0742X; GW0742X; GW610742; GW-610742) is a potent and highly selective PPARβ/δ agonist with potential anti-inflammatory activity.
GW9662 V0826 GW9662 22978-25-2 GW9662 (GW-9662; GW 9662) is an irreversible and selective inhibitor of PPAR (peroxisome proliferator-activated receptor) with potential anticancer activity.
Indeglitazar (PPM 204 and PLX 204) V5144 Indeglitazar (PPM 204 and PLX 204) 835619-41-5 Indeglitazar (formerly PPM-204 and PLX-204) is a novel, potent and orally bioavailable peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ).
Methyl clofenapate V88747 Methyl clofenapate 21340-68-1 Methyl clofenapate (Clofenapate methyl ester; MCP) is a peroxisome proliferator that can induce hypolipidemia, peroxisome proliferation, and hepatocarcinogenesis.
PPARα/γ agonist 2 V51327 PPARα/γ agonist 2 2213365-56-9 PPARα/γ agonist 2 is a novel and potent PPARα full agonist and PPARγ partial agonist.
PPARα/γ agonist 4 V101074 PPARα/γ agonist 4 PPARα/γ agonist 4 (Compound (S)-7) is an orally available dual potent activator of PPARα and PPARγ with EC50 values of 0.061 μM and 1.42 μM, respectively.
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