| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V3885 | Ivosidenib (AG-120) racemate | 1448346-63-1 | Ivosidenib racemate (AG120; RG120; AG-120; RG-120;Tibsovo), the racemic mixture ofIvosidenib, is an orally bioavailable andsmall moleculeIDH1 inhibitor that inhibits mutated cytosolic isocitrate dehydrogenase 1 (IDH1). |
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V0856 | MK-8245 | 1030612-90-8 | MK-8245 (MK8245; MK 8245) is a novel and potentliver-targeted inhibitor of stearoyl-CoA desaturase (SCD) with anti-diabetic and anti-dyslipidemic activities. |
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V0855 | AGI-5198 | 1355326-35-0 | AGI-5198 (also know as IDH-C35; IDHC35; AGI-5198; AGI 5198) is a novel, highly potent and selective inhibitor of IDH1 (isocitrate dehydrogenase 1) R132H/R132C mutants with potential anticancer activity. |
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V0862 | AGI-6780 | 1432660-47-3 | AGI-6780 (AGI6780; AGI 6780) is a potent and selective inhibitor oftumor-associated mutant IDH2 (isocitrate dehydrogenases 2) R140Q with potential anti-inflammatory activity. |
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V139594 | MEDS700 | 2770979-81-0 | MEDS700 is a blood-brain barrier-permeable human dihydroorotate dehydrogenase (hDHODH) inhibitor with an IC50 value of 1.5 nM. |
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V0858 | NCT-501 | 1802088-50-1 | NCT-501 (NCT501; NCT 501), a theophylline-based compound, is a novel, highly potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with potential anticancer activity. |
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V144635 | SARS-CoV-2-IN-115 | 2557232-80-9 | SARS-CoV-2-IN-115 is a SARS-CoV-2 inhibitor. |
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V144717 | SDH-IN-28 | SDH-IN-28 is a succinate dehydrogenase inhibitor with an IC50 value of 2.65 mg/L. | |
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V144718 | SDH-IN-29 | 3085095-22-0 | SDH-IN-29 is an SDH inhibitor with an IC50 value of 0.0709 μM. |
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V144719 | SDH-IN-44 | 3103433-67-3 | SDH-IN-44 is a succinate dehydrogenase (SDH) inhibitor with an IC50 value of 12.5 μg/mL against Alternaria solani. |
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V144742 | Sedaxane | 874967-67-6 | Sedaxane is a novel broad-spectrum seed treatment fungicide. |
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V104906 | Succinate dehydrogenase-IN-5 | Succinate dehydrogenase-IN-5 (compound M8) is an inhibitor of succinate dehydrogenase. Succinate dehydrogenase-IN-5 interferes with the energy metabolism and growth of fungi, and has inhibitory effects on Rhizoctonia solani, Sclerotinia sclerotiorum, Botrytis cinerea, and Fusarium graminearum, with EC50 <0.3μg/mL. | |
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V145393 | Succinate dehydrogenase-IN-9 | Succinate dehydrogenase-IN-9 is a succinate dehydrogenase inhibitor (IC50: 3.6 μM). | |
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V0857 | SW-033291 | 459147-39-8 | SW033291 (SW-033291; SW 033291) is a selective and high affinity inhibitor of the prostaglandin-degrading enzyme 15-PGD (15-hydroxyprostaglandin dehydrogenase) with potential kidney and liver protective effects. |
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V2766 | Vorasidenib | 1644545-52-7 | Vorasidenib (formerly known as AG-881; AG881) is a selective and orally bioavailable inhibitor of mutated forms of both isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) with potential anticancer activity. |
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V147319 | ZG-2492 | 3084810-37-4 | ZG-2492 is an orally effective LDHA inhibitor with an IC50 value of 156 nM. |
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V147474 | α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu | α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu is an oligosaccharide. | |
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V0859 | Disulfiram | 97-77-8 | Disulfiram (Disulfan; NSC 190940;Dicupral; Disetil;NSC190940; Tetraethylthiuram disulfide; TETD)is a potent andspecific inhibitor of aldehyde-dehydrogenase (ALDH1) that is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. |
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V0866 | Gimeracil | 103766-25-2 | Gimeracil (chlorodihydroxypyridine; CDHP; Gimestat), a pyridine/pyridone analog and an approved anticancer drug, is a potent inhibitor of the dihydropyrimidine dehydrogenase (DPYD) enzyme with potential anti-neoplastic activity. |
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V0869 | Isovaleramide | 541-46-8 | Isovaleramide (NPS-1776; NPS 1776; NPS1776; 3-Methylbutanamide), a natural product found in Valeriana pavonii, is a potent anticonvulsant agent that acts as an inhibitor of alcohol dehydrogenases. |