LXR

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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LXR

LXR related products

Cat No.	Product Name	CAS No.	Product Description
V128033	ABCA1 inducer 2	2451589-46-9	ABCA1 inducer 2 is a non-lipophilic ABCA1 inducer.
V3965	Abequolixron (RGX-104)	610318-54-2	Abequolixron (formerly known as SB742881; RG104; SB-742881) is a novel potent and orally bioavailable liver-X nuclear hormone receptor-beta (LXR)agonist with potential immunomodulating and anticancer activities.
V3966	Abequolixron (RGX-104) HCl	610318-03-1	AbequolixronHCl (formerly RGX-104; SB-742881; SB742881), the hydrochloride salt ofRGX104, is a novel potent and orally bioavailable liver-X nuclear hormone receptor-beta (LXR)agonist that modulates innate immunity via transcriptional activation of the ApoE gene.
V3482	BMS-779788	918348-67-1	BMS-779788 (formerlyknown as XL-652, EXEL 04286652 and BMS-788) is a novel and potentLXR (Liver X Receptors)partial agonist withIC50values of 68 nM for LXRαand 14 nM for LXRβ.
V1852	GW3965 HCl	405911-17-3	GW3965 (GW-3965) HCl, the hydrochloride salt ofGW3965, is a novel, potent, selective LXR (liver X receptor) agonist for hLXRα and hLXRβ with potential anti-inflammatory activity.
V2912	LXR623	875787-07-8	LXR623 (WAY-252623; LXR-623) is a novel, highly brain-penetrant, selective and orally bioavailable synthetic modulator of LXR (Liver X receptor) with anticancer activity, It is a partial LXRα and full LXRβ agonist with IC50s of 24 nM and 179 nM, respectively.
V139144	LXRβ ligand 1	171049-41-5	LXRβ ligand 1 is an LXRβ ligand-binding domain agonist with an EC50 of 57 μM and a Ki of 28 μM for human LXRβ.
V1854	SR9243	1613028-81-1	SR9243 (SR-9243) is a potent and selective inverse agonist ofLXR.
V1853	T0901317 (T-1317)	293754-55-9	T0901317 (formerly known as T-1317 or TO-091317 or TO 901317)is a potentand selective liver X receptor (LXR) agonist for multiple targets, which has EC50 values of 20 nM and 5 μM for LXRα and FXR, respectively.
V145953	TFCA	895700-18-2	TFCA is a liver X receptor α (LXRα) antagonist.
V146154	TLC-2716		TLC-2716 is an orally effective intestinal and liver-targeting LXRα and LXRβ inhibitor with EC50 values of 7 nM and 15 nM, respectively.
V60091	Iristectorigenin B	86849-77-6	Iristectorigenin B (Iristectrigenin B) is a liver X receptor (LXR) modulator.