| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V104874 | ATR kinase-IN-3 | 1613196-92-1 | ATR kinase-IN-3 (compound IG-28) is an ATR protein kinase inhibitor with a Ki value of 0.01 to 1 μM, which can be used in tumor research. |
|
V0231 | AZ20 | 1233339-22-4 | AZ20 is a novel potent and selective inhibitor of ATR(ATM and Rad3-related) protein kinase with potential antitumor activity. |
|
V0181 | CB-5083 | 1542705-92-9 | CB-5083 is a novel, potent, selective, first in class and orally bioavailable p97 AAA ATPase inhibitor with potential anticancer activity. |
|
V0230 | CGK-733 | 905973-89-9 | CGK 733 is a novel, potent and selective inhibitor of ATM (ataxia-telangiectasia mutated) and ATR (ATM and Rad3-related)with the potential to treat Hepatocellular carcinoma (HCC). |
|
V2528 | CP-466722 | 1080622-86-1 | CP-466722 is a novel, specific and reversible ATM inhibitor with anIC50value of 4.1 μM, it does not affect ATR and inhibits PI3K or PIKK family members in cells. |
|
V3122 | Elimusertib (BAY-1895344) diHCl | Elimusertib (BAY1895344) diHCl, the dihydrochloride salt of BAY 1895344, is a selective and orally bioavailable ATR (ataxia telangiectasia and Rad3-related) inhibitor with potential antitumor activity. | |
|
V0204 | ETP-46464 | 1345675-02-6 | ETP-46464 (ETP46464) is a novel, potent and selective inhibitor of ATR (Ataxia-telangiectasia mutated) and mTOR (mammalian target of rapamycin) with potential anticancer activity. |
|
V2525 | KU-55933 | 587871-26-9 | KU-55933 is a potent and specific ATM (Ataxia-telangiectasia mutated) kinase inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. |
|
V2526 | KU-60019 | 925701-49-1 | KU-60019 is an improved analogue of KU-55933 with 10-fold higher activity than KU-55933 at blocking radiation-induced phosphorylation of key ATM targets in human glioma cells. |
|
V2527 | VE-821 | 1232410-49-9 | VE-821 is a novel potent and highly selective ATP competitive protein kinase inhibitor of ATR (ataxia telangiectasia mutated and Rad3 related) with Ki and IC50 of 13 nM and 26 nM in cell-free assays, it shows inhibition of H2AX phosphorylation, and had minimal activity against PIKKs ATM, DNA-PK, mTOR and PI3Kγ. |
|
V0232 | Schisandrin B (γ-Schisandrin; Sch B) | 61281-37-6 | Schisandrin B (γ-Schisandrin; Sch B) is a naturally occuring and the most abundant dibenzocyclooctadiene lignan isolated from traditional Chinese medicinal herb Schisandra chinensis (Turcz.) with antioxidant effect on rodent liver and heart. Baill. |
|
V0233 | Ceralasertib (AZD-6738) | 1352226-88-0 | Ceralasertib (formerly AZD6738), amorpholino-pyrimidine-based DNA damage repair agent,is a potent, orally bioavailable and selective inhibitor of ATR (ataxia telangiectasia and rad3 related) kinase with potential antitumor activity. |
|
V2529 | Berzosertib (VE-822; VX-970) | 1232416-25-9 | This product is discontinued due to commercial reason,Berzosertib (VE-822; VX-970; M6620) is a specific ATR inhibitor with IC50 of 19 nM in HT29 cells. |
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