| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V0059 | GSK2606414 | 1337531-36-8 | GSK2606414 is a novel, potent and selective inhibitor of PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) with an IC50 of 0.4 nM and at least 100-fold selectivity over the other EIF2AKs tested. |
|
V0060 | GSK2656157 | 1337532-29-2 | GSK2656157 (GSK-2656157) is a novel, potent, ATP-competitive and highly selective inhibitor of PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) enzyme with IC50 of 0.9 nM in cell-free assays, it has 500-fold greater activity against a panel of 300 kinases. |
|
V0058 | Salubrinal | 405060-95-9 | Salubrinal is a novel, potent,cell-permeable and selective inhibitor of eIF2α (eukaryotic translation initiation factor 2 subunit α) dephosphorylation with potential anticancer activity. |
|
V0061 | ISRIB (trans-isomer) | 1597403-47-8 | ISRIB (trans-isomer), the trans-isomer of ISRIB, is a novel, potent and selective inhibitor of PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) with IC50 of 5 nM. |