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PERK

PERK

PERK related products

Structure Cat No. Product Name CAS No. Product Description
GSK-2606414 V0059 GSK2606414 1337531-36-8 GSK2606414 is a novel, potent and selective inhibitor of PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) with an IC50 of 0.4 nM and at least 100-fold selectivity over the other EIF2AKs tested.
GSK-2656157 V0060 GSK2656157 1337532-29-2 GSK2656157 (GSK-2656157) is a novel, potent, ATP-competitive and highly selective inhibitor of PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) enzyme with IC50 of 0.9 nM in cell-free assays, it has 500-fold greater activity against a panel of 300 kinases.
Salubrinal V0058 Salubrinal 405060-95-9 Salubrinal is a novel, potent,cell-permeable and selective inhibitor of eIF2α (eukaryotic translation initiation factor 2 subunit α) dephosphorylation with potential anticancer activity.
反式-ISRIB V0061 ISRIB (trans-isomer) 1597403-47-8 ISRIB (trans-isomer), the trans-isomer of ISRIB, is a novel, potent and selective inhibitor of PERK (PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase) with IC50 of 5 nM.
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