| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V51265 | CD73-IN-4 | 2216764-29-1 | CD73-IN-4 is a selective, highly effective methylene phosphate CD73 with IC50 of 2.6 nM for human CD73. |
|
V51266 | CD73-IN-5 | 2412019-99-7 | CD73-IN-5 is a potent and specific non-nucleotide small molecule CD73 inhibitor (IC50 = 19 nM). |
|
V119285 | COPCP trisodium | COPCP trisodium (compound 7a) is a potent and selective inhibitor of the 5'-nucleotidase CD73. | |
|
V102565 | MethADP trisodium | 2659222-76-9 | MethADP (adenosine 5'-(α,β-methylene) diphosphate) trisodium is a CD73 inhibitor. |
|
V143452 | PSB-24000 | PSB-24000 is a selective extracellular 5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for human CD73 (481 nM for membrane-bound CD73 in triple-negative breast cancer cells). | |
|
V77719 | Quemliclustat (AB-680) ammonium | AB-680 ammonium is a potent, reversible, and selective CD73 (ectonucleotidase) inhibitor (antagonist) with a Ki of 4.9 pM for hCD73 and selectivity for the related extracellular nucleotidase CD39. | |
|
V144458 | S095024 | S095024 is a humanized IgG1 monoclonal antibody inhibitor that targets CD73. | |
|
V86823 | Uprevstobart | Uprevstobart is a human IgG1 kappa monoclonal antibody against NT5E. | |
|
V147179 | XC-12 | XC-12 is an orally effective, potent small-molecule CD73 inhibitor (an immune checkpoint inhibitor) with IC50 values of 12.36 nM for soluble CD73 and 1.29 nM for membrane-bound CD73. |