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New7 related products

Structure Cat No. Product Name CAS No. Product Description
ACY-1083 V4690 ACY-1083 1708113-43-2 ACY-1083 is a novel, potent, selective and brain-penetrant HDAC6 inhibitor with an IC50 of 3 nM.
ARN 077 V4565 ARN 077 1373625-34-3 ARN 077 (ARN-077) is a novel, potent and selectiveN-acylethanolamine acid amidase (NAAA)inhibitor with anIC50of 7 nM for human NAAA.
Bamirastine V4601 Bamirastine 215529-47-8 Bamirastine (also known as TAK-427),a new imidazopyridazine derivative, is a novelantihistamine compound withantiallergic effects.
BI-3812 V4718 BI-3812 2166387-64-8 BI-3812 (BI3812) is novel, highly potent and efficaciousBCL6inhibitor with potential antitumor activity.
BI8626 V4713 BI8626 1875036-75-1 BI8626 is a novel, potent and specific inhibitor of the ubiquitin ligaseHUWE1with anIC50of 0.9 μM.
CHMFL-BTK-01 V4773 CHMFL-BTK-01 2095280-64-9 CHMFL-BTK-01 (compound 9) is a novel, potent, highly selective and irreversible/covalentBTK (Bruton's tyrosine kinase)inhibitor with anIC50of 7 nM.
Diflapolin V4634 Diflapolin 724453-98-9 Diflapolin is reported to be the first potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor.
Emicerfont V4953 Emicerfont 786701-13-1 Emicerfont (also known asGW876008) is a novel and potent corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50of 66 nM.
FGTI-2734 V4792 FGTI-2734 1247018-19-4 FGTI-2734 is a novel and potent RAS C-terminal mimetic dualfarnesyl transferase (FT)andgeranylgeranyl transferase-1 (GGT)inhibitor that thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors withIC50s of 250 nM and 520 nM forFTandGGT, respectively.
GNE-049 V4551 GNE-049 1936421-41-8 GNE-049 is a novel, highly potent and selective CBP/p300 bromodomaininhibitor with anIC50of 1.1 nM in TR-FRET assay.
IMD-0560 V4746 IMD-0560 439144-66-8 IMD-0560 is a novel and potent IKK inhibitor which suppresses heart failure and chronic remodeling after myocardial ischemia via MMP alteration.
K-Ras G12C-IN-1 V4789 K-Ras G12C-IN-1 1629265-17-3 K-Ras G12C-IN-1 is a novel, potent and irreversible/covalent inhibitor of K-Ras protein with G12C mutation.
KRas G12C抑制剂2 V4785 KRas G12C inhibitor 2 2206735-61-5 KRAS G12C inhibitor 2 is a novel and potent inhibitor of KRAS.
LY-450108 V4865 LY-450108 376594-67-1 LY450108 is a potent AMPA receptor enhancer.
LY223982 V4885 LY223982 117423-74-2 LY 223982 is a novel, potent and specific BLT1 (leukotriene B4) receptor antagonist with anIC50of 13.2 nM against [3H]LTB4 binding to LTB4 receptor.
LY2979165 V4849 LY2979165 1311385-32-6 LY2979165, a novel and potent mGlu2 agonist being developed as an anti-depressant drug candidate, has potential usefulness in the treatment of bipolar disorder.
MEK-IN-1 V4729 MEK-IN-1 870600-45-6 MEK-IN-1 is a MEK inhibitor from patent WO2008076415A1.
MG 1 V4722 MG 1 148274-76-4 MG 1 (MG-1) is a novel and potent α1adrenergic receptorantagonist identified using the quantitative structure-activity relationship model.
Nevanimibe HCl V4818 Nevanimibe HCl 133825-81-7 Nevanimibe HCl (also known as PD-132301 hydrochloride and ATR-101 hydrochloride), the hydrochloride salt ofNevanimibe, is a novel, selective and potent acyl-coenzyme A: cholesterol O-acyltransferase 1 (ACAT1) inhibitor with anEC50of 9 nM.
NSC-305787 HCl V5038 NSC-305787 HCl 53868-26-1 NSC305787 HCl, the hydrochloride salt ofNSC305787, is a novel, potent and selectivesmall molecule inhibitor of ezrin with a Kdof 5.85 μM, it inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50of 8.3 μM, and has antitumor activity.
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