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Phosphodiesterase(PDE)

Phosphodiesterase(PDE)

Phosphodiesterase(PDE) related products

Structure Cat No. Product Name CAS No. Product Description
(1R,2R)-Elpipodect V118458 (1R,2R)-Elpipodect 1424378-99-3 (1R,2R)-Elpipodect ((1R,2R)-MK-8189) is the (1R,2R) type enantiomer of Elpipodect.
(R)-(-)-咯利普兰 V3497 (R)-(-)-Rolipram 85416-75-7 R)-(-)-Rolipram is the R-enantiomer of Rolipram with potent anti-inflammatory and anti-depressant activity in the central nervous system, and it is more potent than its S enantiomer.
(R)-Irsenontrine ((R)-E2027) V72042 (R)-Irsenontrine ((R)-E2027) 1429509-81-8 (R)-Irsenontrine ((R)-E2027) is the R-isomer of Irsenontrine and is a potent inhibitor of phosphodiesterase 9 (PDE9) with IC50 of 0.041 μM.
1,3,5-Trihydroxy-4-prenylxanthone V72077 1,3,5-Trihydroxy-4-prenylxanthone 53377-61-0 1,3,5-Trihydroxy-4-prenylxanthone is a Na+/H+ (Na+/H+ Exchanger (NHE)) exchange system inhibitor (antagonist) with a minimum inhibitory concentration of 10 μg/mL.
3-异丁基-1-甲基黄嘌呤 V4097 3-Isobutyl-1-methylxanthine 28822-58-4 IBMX is anonspecific, broad-spectrum, competitive inhibitor of phosphodiesterase (PDE) inhibitor, withIC50s of 6.5, 26.3 and 31.7 μM forPDE3,PDE4andPDE5, respectively.
4-Nitrophenyl phenylphosphonate V102752 4-Nitrophenyl phenylphosphonate 57072-35-2 4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases.
5,6-DCl-cBIMP V92447 5,6-DCl-cBIMP 129693-10-3 5,6-DCl-cBIMP, a cyclic adenosine monophosphate analog, can act as an agonist of PDE2 and significantly enhance the cAMP and cGMP hydrolysis activity of PDE2.
ATX inhibitor 18 V72072 ATX inhibitor 18 2402772-30-7 ATX inhibitor 18 is a potent ATX inhibitor (antagonist) with IC50 of 24.2 nM.
ATX inhibitor 22 V72089 ATX inhibitor 22 2969213-59-8 ATX inhibitor 22 is a new ATX (autaxin) inhibitor (antagonist) with a corresponding IC50 of 218.9 μM, but lacks LPAR1 inhibitory activity.
ATX inhibitor 8 V72056 ATX inhibitor 8 2156656-37-8 ATX inhibitor 8 is an inhibitor (blocker/antagonist) of the autotaxin (ATX) factor.
Autotaxin-IN-6 V72046 Autotaxin-IN-6 2800898-98-8 Autotaxin-IN-6 (compound 23) is an autotaxin (ATX) inhibitor (antagonist) with IC50 of 30 nM.
BAY 73-6691 racemate V4194 BAY 73-6691 racemate 794568-90-4 BAY 73-6691 racemate is a novel, potent, selective, and brain penetrantPDE9A(Phosphodiesterase 9) inhibitor.
BI-409306 V3770 BI-409306 1189767-28-9 BI 409306 (SUB 166499) isa novel potent, selective and oral phosphodiesterase 9A (PDE9A)inhibitor.
BL-122 V115969 BL-122 1220393-12-3 BL-122 is a selective phosphodiesterase-5 (PDE-5) inhibitor.
Braylin V72079 Braylin 6054-10-0 Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammation and immunomodulation, making it a potential target for studying immuno-inflammatory diseases.
BRD9500 V72024 BRD9500 1630760-75-6 BRD9500 is a potent, orally bioactive phosphodiesterase 3 (PDE3) inhibitor (antagonist) with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively.
BRL-50481 V4092 BRL-50481 433695-36-4 BRL-50481 is a novel, potent and selective inhibitor ofphosphodiesterase 7(PDE7) withIC50s of 0.15, 12.1, 62 and 490 μM forPDE7A,PDE7B,PDE4andPDE3, respectively.
Deltasonamide 2 hydrochloride V72017 Deltasonamide 2 hydrochloride 2448341-55-5 Deltasonamide 2 HCl is a competitive, high-affinity inhibitor of PDEδ with Kd of ~385 pM.
Denbufylline V87666 Denbufylline 57076-71-8 Denbufylline (BRL 30892) is a phosphodiesterase-4 (PDE4) inhibitor.
Doxofylline-d4 (doxofylline d4) V72083 Doxofylline-d4 (doxofylline d4) 1346599-13-0 Doxofylline-d4 is the deuterium labelled form of Doxofylline.
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