| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V0294 | 2-Methoxyestradiol (2MeOE2, NSC659853, 2ME2) | 362-07-2 | 2-Methoxyestradiol (2-MeOE2, NSC-659853, 2-ME2; 2-ME), an endogenous/natural metabolite ofestradiol [17β-estradiol (E2)], is a potent inhibitor of tubulin with potential anticancer activity. |
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V1607 | ABT-751 (E 7010) | 141430-65-1 | ABT-751 (also known as ABT751;E-7010;E7010) is a novel, potent,sulfonamide-basedand orally bioavailable antimitotic/antitubulinagent or tubulin inhibitor/microtubule destablizer with potential antitumor activity. |
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V1616 | CK-636 (CK-0944636) | 442632-72-6 | CK-636 (also called CK636;CK-0944636;CK0944636)is a potent inhibitor of the actin-related protein(Arp2/3) complex with IC50 values of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively. |
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V1618 | CW069 | 1594094-64-0 | CW069 (CW-069; CW 069) is a potent, selective and allosteric inhibitor of microtubule motor protein HSET with potential antitumor activity. |
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V1614 | INH1 (IBT13131) | 313553-47-8 | INH1 (also calledIBT-13131;INH-1; IBT13131) is a potent and cell-permeable Hec1 (High expression in cancer 1) inhibitor with potential anticancer activity. |
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V1613 | INH6 | 1001753-24-7 | INH6 (INH-6; INH 6) is a novel, potent and cell-permeable inhibitor of High expression in cancer 1 (Hec1) with potential anticancer activity. |
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V3031 | SMART | 1135797-91-9 | SMART is a highly potent tubulin inhibitor with IC50 in the nanomolar range (20-30 nM) in a number various cancer cell lines including prostate cancer and melanoma cells. |
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V1612 | TAI-1 | 1334921-03-7 | TAI-1 (TAI 1; TAI1) is a selective Hec1 (High expression in cancer 1) inhibitor with potential anticancer activity. |
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V1624 | Triclabendazole (CGA89317) | 68786-66-3 | Triclabendazole (also known as CGA-89317; CGA89317; EGA-230B; Fasinex; NVP-EGA-230; Egaten)is a benzimidazole-based anthelmintic and fasciolicidal agentthat acts as a tubulin inhibitor by binding to tubulin and impairing the intracellular transport mechanisms, thus interfering with protein synthesis. |
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V1611 | Docetaxel Trihydrate (RP 56976) | 148408-66-6 | DocetaxelTrihydrate (formerly RP-56976; NSC-628503; trade name Taxotere), the trihydrated form of docetaxel which is a paclitaxel analog, is a tubulin/mitotic inhibitor with a broad spectrum of antineoplastic activities. |
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V1622 | Lexibulin (CYT-997) | 917111-44-5 | CYT997 (also called Lexibulin; CYT-997; CYT 997) is a potent VDA-vascular disrupting agent and also apotent microtubule polymerization/mitotic inhibitor with potential anticancer activity. |
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V1609 | Cabazitaxel (XRP-6258; RPR-116258A; taxoid XRP6258) | 183133-96-2 | Cabazitaxel (formerly known as RPR-116258A, XRP-6258, TXD-258; Jevtana) is a semi-synthetic and marketed taxane analog (the natural taxoid 10-deacetylbaccatin III) with potential anticancer activity and improved pharmacological profiles (e. |
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V1619 | Epothilone A (Epo A) | 152044-53-6 | Epothilone A (also abbreviated as Epo A), similar to paclitaxel in terms of mechanism of action, is also a naturally occurring microtubule-stabilizing macrolide agent (also called mitotic inhibitor or tubulin inhibitor) isolated from the myxobacteriumSorangium cellulosum with potential antineoplastic activity. |
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V1604 | Docetaxel (RP 56976) | 114977-28-5 | Docetaxel (formerly known as RP56976;NSC628503; RP-56976;NSC-628503;Taxotere), a semisynthetic analog ofpaclitaxel and approved anticancer drug, is a mitotic inhibitor and tubulin inhibitor that inhibits the depolymerization of microtubules by binding to and stabilizing microtubules. |
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V1606 | Epothilone B (EPO 906; Patupilone) | 152044-54-7 | Epothilone B (formerly known as EO-906;patupilone;EPO 906A; EPO906, Patupilone) is a paclitaxel-class of microtubule-stabilizing agent (also called mitotic inhibitor or tubulin inhibitor) with potential antitumor activity and has been approved for cancer treatment. |
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V1610 | Combretastatin A4 (CA-4; CRC 87-09) | 117048-59-6 | Combretastatin A4 (CA-4; CRC-87-09; Combretastatin A-4) is a highly potent tubulin/microtubuleinhibitor or microtubule polymerization destablizer with potential antitumor activity. |
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V1623 | Griseofulvin (Grifulvin) | 126-07-8 | Griseofulvin (Gris-PEG; Grifulvin; Fulvicin, Grisactin, Amudane), a naturally occurring spirocyclic compound isolatedfrom some strains of the mold Penicillium griseofulvumam, is an oral antifungal medication approved for use in the treatment of various dermatophytoses (ringworm) such as fungal infections of the nails and skin when antifungal creams did not work. |
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V1603 | Paclitaxel (Taxol) | 33069-62-4 | Paclitaxel (also known as NSC-125973; BMS-181339-01;trade name taxol; Anzatax; Asotax; Bristaxol)is a highly potent microtubule polymer stabilizer (mitotic inhibitor that stabilizes the polymerization of tubulin) with an IC50 of 0.1 pM in human endothelial cells. |
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V1608 | Nocodazole (Oncodazole; R17934) | 31430-18-9 | Nocodazole (Oncodazole; R-17934;R17934) is a potent and rapidly-reversible inhibitor of microtubule polymerization/microtubule destablizer, the so called antimitotic or antitubulin agent, with potential antineoplastic activity. |
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V1621 | Vinblastine (Vincaleukoblastine) | 865-21-4 | Vinblastine (formerly NSC49842; NSC-49842;NSC 49842; Velban; Velsar; VLB; Vincaleukoblastine), a naturally occuring alkaloid isolated from the plant Vinca rosea Linn, is an approved anticancer drug acting as a potent mitotic inhibitor thatinhibits microtubule assembly/formation. |
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