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Complement System

Complement System

Complement System related products

Structure Cat No. Product Name CAS No. Product Description
ARC186 sodium V86833 ARC186 sodium ARC186 (sodium) is a PEGylated nucleic acid aptamer.
Avacincaptad pegol V74790 Avacincaptad pegol 1613641-69-2 Avacincaptad pegol (Izervay) is a nucleic acid aptamer that works as a C5 complement inhibitor to reduce inflammation-related retinal pigment epithelial (RPE) damage.
Bisphenol A bissulfate disodium V119513 Bisphenol A bissulfate disodium 10040-44-5 Sodium bisulfate of bisphenol A is a metabolite of bisphenol A.
BuChE-IN-23 V130739 BuChE-IN-23 3067571-93-8 BuChE-IN-23 is an orally effective, blood-brain barrier-crossing butyrylcholinesterase (eqBuChE) inhibitor with an IC50 of 15.59 μM and a Ki of 29.33 μM.
C1s-IN-1 trihydrochloride V130873 C1s-IN-1 trihydrochloride 1376162-36-5 C1s-IN-1 trihydrochloride is a selective inhibitor of C1s protease with a Ki value of 5.8 μM.
C5aR1 antagonist 1 V86829 C5aR1 antagonist 1 2365325-67-1 C5aR1 antagonist 1 (compound 7e) is an orally available C5aR antagonist.
Cemdisiran sodium scrambled negative control V131368 Cemdisiran sodium scrambled negative control The scrambled negative control is a negative control for Cemdisiran sodium with its sequence scrambled.
Cevolisiran sodium scrambled negative control V131428 Cevolisiran sodium scrambled negative control Cevolisiran sodium scrambled negative control is a negative control with the sequence of Cevolisiran sodium scrambled.
Complement factor D-IN-2 V3627 Complement factor D-IN-2 1903742-34-6 Complement factor D-IN-2 (extracted fromWO2015130838A1, compound 190) is an inhibitor of complement factor D with the potential to be used for treating autoimmune diseases.
MK-4721 V140031 MK-4721 MK-4721 is a fully human IgG1κ monoclonal antibody targeting PSCA with a Ka value of 0.2 nM.
Omoprubart V141898 Omoprubart 2763342-87-4 Omoprubart is a recombinant humanized monoclonal antibody against C5 complement.
PIC1 PA TFA V142708 PIC1 PA TFA PIC1 PA TFA is the trifluoroacetate form of PIC1 PA.
PMX 205 Trifluoroacetate V76618 PMX 205 Trifluoroacetate PMX 205 Trifluoroacetate is a potent complement C5a receptor (C5aR; CD88) antagonist.
Refinicopan V143979 Refinicopan 2922808-66-8 Refinicopan is a complement factor D inhibitor with an IC50 value of 10 nM.
Riliprubart (SAR 445088) V74797 Riliprubart (SAR 445088) 2756228-76-7 Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody (mAb) that can inhibit activated C1s in the proximal part of the classical complement system.
RPARPAR V144383 RPARPAR 1184942-81-1 RPARPAR is a CendR tumor-penetrating peptide.
RPARPAR acetate V144384 RPARPAR acetate RPARPAR acetate is a CendR tumor-penetrating peptide.
Ruxoprubart V144427 Ruxoprubart 2842046-67-5 Ruxoprubart is a complement factor B (Bb subunit) inhibitor.
Sefaxersen sodium V144746 Sefaxersen sodium 2272983-11-4 Sefaxersen sodium is a specific antisense oligonucleotide (ASO) that targets complement factor B (CFB).
Tanruprubart V145579 Tanruprubart 2065212-40-8 Tanruprubart is a C1q inhibitor and C1q depletor.
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