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Bcl-2

Bcl-2

Bcl-2 related products

Structure Cat No. Product Name CAS No. Product Description
(R)-(-)-醋酸棉酚 V0006 AT101 866541-93-7 AT-101 [(R)-(-)-Gossypol acetic acid,the levorotatory isomer of a natural product Gossypol],is a novel, oral and potent inhibitor of Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; it shows no inhibition against BIR3 and BID.
(S)-Sabutoclax ((S)-BI-97C1) V85889 (S)-Sabutoclax ((S)-BI-97C1) 1228178-73-1
A-1210477 V0010 A-1210477 1668553-26-1 A-1210477 is anovel, potent and specific MCL-1 (Myeloid cell leukemia-1) inhibitor with Ki and IC50 of 0.45 nM and 26.2 nM, respectively.
ABBV-467 V76047 ABBV-467 2287186-66-5 ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM).
ABT-737 V0002 ABT-737 852808-04-9 ABT-737 is a novel, potent,selective and orally bioavailable BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in enzymatic assays, respectively.
AF151 V128364 AF151 AF151 is a METTL3 PROTAC degrader with a DC50 of 0.43 μM in MOLM-13 cells.
AMG-176 V3448 AMG-176 1883727-34-1 AMG-176 (AMG176; tapotoclax) is a novel, potent, selective and orally bioavailable inhibitor of MCL-1 (myeloid cell leukemia-1) with aKiof 0.13 nM.
AS 1411 sodium scrambled negative control V129480 AS 1411 sodium scrambled negative control The AS 1411 sodium scrambled negative control is a negative control with the AS 1411 sodium ion sequence scrambled.
AZD4320 V4260 AZD4320 1357576-48-7 AZD4320 is a novel, potent BH3-mimic and dualinhibitor of BCL2/BCLxL withIC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively.
BAD (103-127) (human), FAM-labeled TFA V118586 BAD (103-127) (human), FAM-labeled TFA BAD (103-127) (person), TFA marked with FAM is person BAD (103-127) with FAM tag.
Bak BH3 (72-87), TAMRA-labeled V78338 Bak BH3 (72-87), TAMRA-labeled Bak BH3 (72-87), TAMRA-labeled is a biologically active peptide.
Bcl-2-IN-3 V129936 Bcl-2-IN-3 383860-03-5 Bcl-2-IN-3 is a Bcl-2 inhibitor.
Beclanorsen sodium V116785 Beclanorsen sodium Beclanorsen sodium is an antisense oligonucleotide that targets Bcl-2 mRNA.
BI-97C1 V0008 sabutoclax (BI 97C1) 1228108-65-3 Sabutoclax (BI-97C1),a derivative of apogossypolone, is a novel and potent pan-Bcl-2 inhibitor with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM forBcl-xL, Bcl-2, Mcl-1 and Bfl-1, respectively.
BTSA1 V3168 BTSA1 314761-14-3 BTSA1 (BTSA-1) is a novel and potent BAX (BCL2-associated X protein) activator with antitumor activity.
FKL-137 V136067 FKL-137 FKL-137 is an inhibitor of the GLUT1 and PI3K/AKT signaling pathways.
Gossypol-13C2 (BL 193-13C2) V78509 Gossypol-13C2 (BL 193-13C2) Gossypol-13C2 (BL 193-13C2) is an active compound.
GPER/Bcl-2-IN-1 V136858 GPER/Bcl-2-IN-1 GPER/Bcl-2-IN-1 is a GPER/Bcl-2 inhibitor.
Himachalol V137369 Himachalol 1891-45-8 Himachalol is a sesquiterpene compound found in cedar (Cedrus deodara) wood. It has oral activity and possesses antispasmodic and anticancer properties.
Longan cerebroside II V138986 Longan cerebroside II 220873-86-9 Longan cerebroside II is a cerebroside extracted from Typhonium giganteum.
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