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HDAC

HDAC

HDAC related products

Structure Cat No. Product Name CAS No. Product Description
(S)-HDAC-IN-102 V122172 (S)-HDAC-IN-102 748159-43-5 (S)-HDAC-IN-102 is an HDAC8 inhibitor and an isomer of HDAC-IN-102.
4-溴苯甲酸-2-丁基酰肼 V4087 UF010 537672-41-6 UF010 (UF-010; UF 010) is a novel, potent and selective class I HDAC inhibitor with potential anticancer activities.
4-苯基丁酸钠盐 V0284 Sodium Phenylbutyrate (4-PBA sodium) 1716-12-7 Sodium phenylbutyrate (4-Phenylbutyric acid sodium; 4-PBA sodium),an orphan drug marketed by Ucyclyd Pharma, is a novel and potent histone deacetylase (HDAC) inhibitor used as an as adjunctive therapy for chronic treatment of urea cycle disorders involving deficiencies of argininosuccinic acid synthetase (AS), ornithine transcarbamylase (OTC), or carbamylphosphate synthetase (CPS).
4SC-202 V0264 Domatinostat (4SC202) 910462-43-0 Domatinostat (formerly 4SC-202)is a novel, potent, and orally bioavailable benzamide-based Class I HDAC inhibitor with potential anticancer activity.
Acefylline piperazine V97450 Acefylline piperazine 18833-13-1 Acetylphylline piperazine is a xanthine derivative and adenosine receptor antagonist.
ACY-738 V2907 ACY-738 1375465-91-0 ACY-738 (ACY738) is a novel, potent, selective, brain penetrable and orally-bioavailable HDAC6 inhibitor with neuroprotective and anticancer activities.
AR-42 抑制剂 V0283 AR-42 (HDAC-42, NSC-736012, OSU-42) 935881-37-1 AR-42 (HDAC-42, NSC-736012, OSU-42 etc.) is a novel and potent histone deacetylase (HDAC) inhibitor with potential antitumor activity. At 30 nM, its IC50 inhibits HDAC.
BG45 V0262 BG45 926259-99-6 BG45 (BG-45) is a novel, potent and selective class I HDAC inhibitor with potential anticancer activity.
BRD73954 V0263 BRD73954 1440209-96-0 BRD73954 (BRD-73954) is a novel, potent and dual inhibitor of histone deacetylase 6 (HDAC6) and HDAC8 with potential anticancer activity.
CAY10603 V0267 CAY10603 1045792-66-2 CAY10603 is a novel, potent and selective HDAC6 (Histone deacetylase) inhibitor with potential anticancer activity and a potential to treatneurodegenerative diseases.
CAY10683 (Santacruzamate A) V2867 CAY10683 (Santacruzamate A) 1477949-42-0 Santacruzamate A (also known as CAY10683) is a potent and selective inhibitor of HDAC (histone deacetylase) with IC50 of 119 pM for HDAC2, it exhibits >3600-fold selectivity over other HDACs.
CUDC-101 V0277 CUDC-101 1012054-59-9 CUDC-101 is a novel, potent and multi-targeted histone deacetylase (HDAC) inhibitor with potential anticancer activity.
DLC-50 V88739 DLC-50 2928537-98-6 DLC-50 is a dual inhibitor of PARP-1 and HDAC-1 with IC50 of 1.2 nM and 31 nM, respectively.
DNMT1/HDAC-IN-1 V96662 DNMT1/HDAC-IN-1 DNMT1/HDAC-IN-1 (Compound (R)-23a) is a DNMT1/HDAC dual inhibitor (HDAC1: IC50=0.05 μM), HDAC1 is a major HDAC isoform that interacts with DNMT1 in multiple protein complexes to silence the transcription of TSGs.
Givinostat盐酸盐 V3844 Givinostat HCl 199657-29-9 Givinostat (ITF-2357 hydrochloride)is a potent andorally bioactive HDAC inhibitor with potential anti-inflammatory, anti-angiogenic, and anticancer activities.
HDAC-IN-72 V88675 HDAC-IN-72 763066-77-9 HDAC-IN-72 (compound 7j) is a potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound.
HDAC-IN-93 V118306 HDAC-IN-93 HDAC-IN-93 is an HDAC inhibitor with good pan-HDAC inhibitory activity.
HDAC/HSP90-IN-1 V109166 HDAC/HSP90-IN-1 2244714-37-0 HDAC/HSP90-IN-1 (compound 20) is a potent dual inhibitor of HDAC (IC50 = 194 nM) and HSP90 (HSP90α IC50 = 153 nM).
HDAC/PSMD14-IN-1 V137170 HDAC/PSMD14-IN-1 3062141-62-9 HDAC/PSMD14-IN-1 is a thiorutin derivative.
HDAC1-IN-12 V109219 HDAC1-IN-12 HDAC1-IN-12 is an inhibitor of Plasmodium falciparum HDAC1 (PfHDAC1) with an IC50 value of 4.1 nM.
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