yingweiwo
  1. Home
  2. Products
  3. Signaling Pathways
  4. Protein Tyrosine Kinase
  5. Trk receptor

Trk receptor

Trk receptor

Trk receptor related products

Structure Cat No. Product Name CAS No. Product Description
1D228 V78306 1D228 1D228 is a c-Met/TRK inhibitor (antagonist) with anti-tumor activity.
ANA-12 V0642 ANA-12 219766-25-3 ANA-12 (ANA12) is a novel, potent and selective TrkB inhibitor/antagonist with important biological activity.
Cyclotraxin B TFA V78959 Cyclotraxin B TFA Cyclotraxin B TFA is a cyclic peptide that is a potent and specific TrkB inhibitor (antagonist) without altering BDNF binding.
Gambogic amide V85257 Gambogic amide 286935-60-2 Gambogic amide is a potent and selective TrkA agonist
GNF 5837 V0641 GNF-5837 1033769-28-6 GNF-5837 (GNF5837) is an orally bioavailable pan-TRK (TrkA, TrkB)inhibitor with potential antitumor activity.
GW441756 V0640 GW441756 504433-23-2 GW441756 (GW-441756) is a novel, potent and selective inhibitor of TrkA (Tropomyosin-related kinase A) with potential anticancer activity.
IGF-1R modulator 1 V87856 IGF-1R modulator 1 2375424-89-6 IGF-1R modulator 1 (Example 5) is an IGF-1R modulator with EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB).
PF-06273340 V2756 PF-06273340 1402438-74-7 PF-06273340 is a potent, selective, and well-tolerated pan-Trk inhibitor with IC50 of 6, 4, 3 nM for TrkA, TrkB, Trk C respectively.
Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside V142593 Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside 88510-11-6 Phenylmethyl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside is a nerve growth factor (NGF) secretion promoter found in plants of the genus Piper.
Protein kinase inhibitor 5 V69599 Protein kinase inhibitor 5 2278204-94-5 Protein kinase inhibitor 5 is a potent TRK-A inhibitor (antagonist) with IC50 of 1.8 nM.
TRK-IN-12 V69589 TRK-IN-12 2823342-34-1 TRK-IN-12 (Compound 9e) is a potent TRK inhibitor (TRKG595R IC50 = 13.1 nM).
Trk-IN-2 V146554 Trk-IN-2 1614229-04-7 Trk-IN-2 is a pan-Trk kinase inhibitor with an IC50 of 9 nM against TrkA enzyme and a cellular IC50 of 7 nM, and it is also orally active.
TRK-IN-22 V81625 TRK-IN-22 TRK-IN-22 (compound 11) is an inhibitor (blocker/antagonist) of TRK.
TRK-IN-31 V146555 TRK-IN-31 TRK-IN-31 is an orally effective TRK inhibitor with an IC50 value of 1.8 nM.
TRK-IN-31 hydrochloride V146556 TRK-IN-31 hydrochloride TRK-IN-31 hydrochloride is an orally effective TRK inhibitor with an IC50 value of 1.8 nM.
TRK-IN-34 V146558 TRK-IN-34 2489327-91-3 TRK-IN-34 is an orally effective inhibitor of TRK and TRKC mutant kinases, with IC50 values of 0.75 nM and 0.96 nM for TRKAG595R and TRKAG667C, respectively.
TrkA-IN-10 V146550 TrkA-IN-10 TrkA-IN-10 is a TrkA inhibitor with IC50 values of 17 nM, 8 nM, and 5 nM for TrkA, TrkB, and TrkC, respectively.
TrkA-IN-7 V146551 TrkA-IN-7 296888-45-4 TrkA-IN-7 is an inhibitor of tropomyosin receptor kinase A (TrkA) with a Kd value of 40 μM.
TrkA-IN-8 V146552 TrkA-IN-8 128889-33-8 TrkA-IN-8 is a TrkA inhibitor with a Kd value of 3.3 µM.
TrkC-IN-1 V146553 TrkC-IN-1 1877313-32-0 TrkC-IN-1 is a TrkC inhibitor.
Contact Us
Tel: 1-708-310-1919 Fax: 1-708-557-7486 Email: [email protected] Frequently Asked Questions
Subscribe to our E-newsletter
Name
E-mail

Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved

linkedin facebook
Contact Us
Home Product Cart Member