Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V55536 | 2',3',5'-Tri-O-benzoyl-5-difluoromethyluridine | 2305416-06-0 | 2',3',5'-Tri-O-benzoyl-5-difluoromethyluridine is a thymidine analogue. | |
V56012 | 2',3',5'-Tri-O-benzoyl-5-hydroxy methyluridine (see GL100342) | 53910-92-2 | 2',3',5'-Tri-O-benzoyl-5-hydroxy methyluridine (see GL100342) is a thymidine analog. | |
V75544 | 2',3',5'-Tri-O-benzoyl-5-hydroxymethyl-2'-β-C-methyluridine | 2305416-16-2 | 2',3',5'-Tri-O-benzoyl-5-hydroxymethyl-2'-β-C-methyluridine is a thymidine analogue. | |
V75628 | 2',3',5'-Tri-O-benzoyl-5-iodouridine | 2880-91-3 | 2',3',5'-Tri-O-benzoyl-5-iodouridine is an analogue of purine nucleoside. | |
V55986 | 2',3',5'-Tri-O-benzoyl-5-methoxyuridine | 37805-86-0 | 2',3',5'-Tri-O-benzoyl-5-methoxyuridine is an analogue of purine nucleoside. | |
V75681 | 2',3',5'-Tri-O-benzoyl-6-azauridine | 1627-29-8 | 2',3',5'-Tri-O-benzoyl-6-azauridine is an analogue of purine nucleoside. | |
V55948 | 2',3',5'-Tri-O-benzyl-4'-thio-arabinouridine | 267665-69-0 | 2',3',5'-Tri-O-benzyl-4'-thio-arabinouridine is an analogue of purine nucleoside. | |
V55790 | 2′,3′-Anhydroadenosine | 2627-64-7 | 2′,3′-Anhydroadenosine is an analogue of purine nucleoside. | |
V55811 | 2',3'-Bis(O-(t-butyldimethylsilyl)-5-methoxyuridine | 2305415-94-3 | 2',3'-Bis(O-(t-butyldimethylsilyl)-5-methoxyuridine is an analogue of purine nucleoside. | |
V55817 | 2',3'-Bis(Ot-butyldimethylsilyl)-2-thiouridine | 2305415-97-6 | 2',3'-Bis(Ot-butyldimethylsilyl)-2-thiouridine is an analogue of purine nucleoside. | |
V55636 | 2',3'-Bis(Ot-butyldimethylsilyl)-4',5'-didehydro-5'-deoxyuridine | 128070-78-0 | 2',3'-Bis(Ot-butyldimethylsilyl)-4',5'-didehydro-5'-deoxyuridine is a uridine nucleoside analogue. | |
V55526 | 2',3'-Bis-(Ot-butyldimethylsilyl)uridine | 69504-12-7 | 2',3'-Bis-(Ot-butyldimethylsilyl)uridine is an analogue of purine nucleoside. | |
V75692 | 2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy guanosine | 2389988-71-8 | 2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy guanosine is an analogue of purine nucleoside. | |
V55940 | 2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy-3'-fluoroguanosine | 2389988-77-4 | 2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy-3'-fluoroguanosine is an analogue of purine nucleoside. | |
V75648 | 2',3'-Di-O-acetyl-D-uridine (acetic acid 4-acetoxy-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl- tetrahydrofuran-3-yl ester) | 29108-90-5 | 2',3'-Di-O-acetyl-D-uridine is an analogue of purine nucleoside. | |
V53304 | 2′,3′-Di-O-acetylguanosine | 42167-65-7 | 2′,3′-Di-O-acetylguanosine is a nucleoside analog. | |
V55956 | 2',3'-Di-O-isopropylidene-4'-alpha-C-azidouridine | 690271-27-3 | 2',3'-Di-O-isopropylidene-4'-alpha-C-azidouridine is a uridine analog. | |
V55992 | 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine | 15379-29-0 | 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is an analogue of purine nucleoside. | |
V55500 | 2',3'-Didehydro-2',3'-dideoxyuridine | 5974-93-6 | 2',3'-Didehydro-2',3'-dideoxyuridine is an analogue of purine nucleoside. | |
V75719 | 2′,3′-Dideoxy-3′-fluoro-5-methylcytidine | 115249-95-1 | 2′,3′-Dideoxy-3′-fluoro-5-methylcytidine is an analogue of purine nucleoside. |