Procollagen C Proteinase

Procollagen C Proteinase

Procollagen C proteinase (PCP) and its enhancer protein (PCPE) are key to collagen fibril-assembly and extracellular matrix formation. The carboxyl-propeptides of procollagen types I, II, and III are broken down by PCP, which starts the formation of collagen fibrils on its own. Pro-lysyl oxidase, laminin 5, and type V procollagen N-propeptides may also be broken down by PCP. PCPE, a glycoprotein that binds to the C-propeptide of type I procollagen through its N-terminal CUB domains, stimulates PCP's processing of procollagen. TGF-like growth factors can be activated by proteases related to PCP/BMP-1. In addition to their function in the formation of collagen fibrils, PCPs perform significant biological tasks.

Procollagen C Proteinase related products

Structure Cat No. Product Name CAS No. Product Description
V27826 UK-383367 348622-88-8 UK-383367 (UK383367; UK 383367) is a novel and potent nonpeptide inhibitor of BMP-1(bone morphogenetic protein 1, also called procollagen C-proteinase; PCP) with dermal anti-scarring activity.
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