A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V76266 | (+)-Pinoresinol diacetate | 32971-25-8 | (+)-Pinoresinol diacetate is a naturally occurring compound extracted from Sambucus williamsii and has antifungal activity. |
|
V35082 | (-)-Bornyl acetate ((-)-bornyl acetate; L-(-)-Bornyl acetate) | 5655-61-8 | (-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active isomer of (+)-Bornyl acetate found in hyssop oil. |
|
V56258 | (2R,4S)-Hydroxy Itraconazole-d5 ((2R,4S)-R-63373-d5) | 1217524-77-0 | (2R,4S)-Hydroxy Itraconazole-d5 is the deuterium labelled form of (2R,4S)-Hydroxy Itraconazole. |
|
V56366 | (2R,4S)-Hydroxy Itraconazole-d8 ((2R,4S)-R-63373-d8) | 1217516-26-1 | (2R,4S)-Hydroxy Itraconazole-d8 is the deuterium labelled form of (2R,4S)-Hydroxy Itraconazole. |
|
V76259 | (E)-β-Farnesene (trans-β-Farnesene) | 18794-84-8 | (E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon present in Phlomis aurea Decne essential oil. |
|
V56367 | (Rac)-Paclobutrazol-15N3 | 2642083-16-5 | (Rac)-Paclobutrazol-15N3 is 15N labeled Rac-Paclobutrazol. |
|
V52916 | (S,S)-Valifenalate ((S,S)-IR5885; (S,S)-Valiphenal) | 283159-94-4 | (S,S)-Valifenalate ((S,S)-IR5885) is an amic acid fungicide used to inhibit various fungi of the class Oomycetes. |
|
V53979 | (Z)-Fluoxastrobin | 887973-21-9 | (Z)-Fluoxastrobin is a fungicide. |
|
V53060 | (Z)-Lanoconazole | 101529-65-1 | (Z)-Lanoconazole is the Z configuration form of Lanoconazole. |
|
V52841 | (±)-Pinoresinol | 4263-88-1 | (±)-Pinoresinol is a potent antifungal compound/agent. |
|
V53960 | 1,3,6-Trihydroxy-5-methoxyxanthone | 41357-84-0 | 1,3,6-Trihydroxy-5-methoxyxanthone is a naturally occurring compound that can be extracted from the root bark of Tovomita krukovii. |
|
V41079 | 1-Dodecylimidazole (N-Dodecylimidazole) | 4303-67-7 | 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomally active detergent and cytotoxic agent. |
|
V53927 | 1-O-Methylemodin | 3775-08-4 | 1-O-Mmethylemodin is a naturally occurring compound extracted from Zopfiella longicaudata. |
|
V53928 | 1-Phenylsemicarbazide (2-phenylhydrazinecarboxamide) | 103-03-7 | 1-Phenylsemicarbazide is an antifungal compound/agent. |
|
V54011 | 16,17-Dihydroheronamide C | 2698333-36-5 | 16,17-Dihydroheronamide C has antifungal activity and was designed as a probe for analysis of the mode of action of heronamide C. |
|
V53975 | 2,2-Dibromopropanoic acid | 594-48-9 | 2,2-Dibromopropanoic acid is a dibromoproduct based on propanoic acid. |
|
V53906 | 2,4′-Dichloroacetanilide | 3289-75-6 | 2,4′-Dichloroacetanilide is a fungus inhibitor. |
|
V52519 | 2,6-Dihydroxy-4-methoxyacetophenone | 7507-89-3 | 2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin that can be extracted from the root tissue of Sanguisorba minor. |
|
V54019 | 2-Dodecanol (2-Dodecanol standard) | 10203-28-8 | 2-Dodecanol inhibits hyphal formation and SIR2 expression in C. albicans. |
|
V56194 | 2-Methoxybenzaldehyde-d3 (o-Anisaldehyde-d3) | 56248-49-8 | 2-Methoxybenzaldehyde-d3 is the deuterated form of 2-Methoxybenzaldehyde. |
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