Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V78373 | Netupitant N-oxide-d6 | Netupitant N-oxide-d6 is the deuterium labelled form of Netupitant N-oxide. | |
|
V3789 | Niraparib metabolite M1 | 1476777-06-6 | Niraparib metabolite M1 is a carboxylic acid metabolite of niraparib (MK4827; Zejula), which is a PARP1/2 inhibitor approved for cancer treatment. |
|
V72204 | Nordoxepin hydrochloride (Desmethyldoxepin hydrochloride) | 2887-91-4 | Nordoxepin HCl is the major metabolite of doxepin. |
|
V72189 | Nordoxepin-d3 hydrochloride (Desmethyldoxepin-d3 (hydrochloride)) | 1331665-54-3 | Nordoxepin-d3 ( HCl) is the deuterated form of Nordoxepin HCl. |
|
V50927 | Norendoxifen | 1308808-22-1 | nonsteroidal aromatase inhibitor; tamoxifen metabolite |
|
V72297 | Norzopiclone (N-Desmethyl zopiclone; RP 32273) | 59878-63-6 | Norzopiclone is the inactive (non-active) metabolite of Zopiclone. |
|
V72152 | O-Demethyl Lenvatinib | 417717-04-5 | O-Demethyl Lenvatinib is a metabolite of Lenvatinib. |
|
V76683 | O-Demethyl Lenvatinib hydrochloride | O-Demethyl Lenvatinib HCl is a metabolite of Lenvatinib. | |
|
V80987 | O-desmethyl Mebeverine acid-d5 hydrochloride | O-desmethyl Mebeverine acid-d5 ( HCl) is the O-desmethyl Mebeverine acid deuterated compound standard. | |
|
V71257 | O-Desmethyl Mebeverine alcohol hydrochloride (Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride) | 856620-39-8 | O-Desmethyl Mebeverine alcohol HCl is a metabolite of Mebeverine, a potent α1 receptor (α1 receptor) inhibitor used as an antispasmodic drug in the digestive tract. |
|
V72123 | Ochratoxin α | 19165-63-0 | Ochratoxin α Ochratoxin A A low-toxic photolytic and thermal degradation product. |
|
V72255 | Olmesartan ethyl ester (olmesartan medoxomil ethyl ester impurity) | 144689-23-6 | Olmesartan ethyl ester (compound 11) is an impurity of Olmesartan. |
|
V72126 | Omeprazole sulfide-d3 (Ufiprazole-d3) | 922730-98-1 | Omeprazole sulfide-d3 is the deuterium labelled form of Omeprazole sulfide. |
|
V16457 | Oseltamivir carboxylate (GS 4071; Ro 64 0802) | 187227-45-8 | Oseltamivir acid (GS 4071), the bioactive metabolite of Oseltamivir phosphate, is an orally bioavailable and selective inhibitor of influenza virus neuraminidase (IC50=2 nM), active against both influenza viruses A and B. |
|
V60038 | Osimertinib Impurity C(Rezivertinib analogue 1) | 2227103-37-7 | Rezivertinib analog 1 is a process impurity in osimertinib mesylate and may be utilized in study/research of non-small cell lung cancer. |
|
V72214 | p,p'-DDD-d8 (4,4'-DDD-d8; p,p'-Dichlorodiphenyl dichloroethane-d8) | 93952-20-6 | p,p'-DDD-d8 is the deuterium labelled form of p,p'-DDD. |
|
V67618 | p,p'-DDE-d8 (4,4'-DDE-d8; p,p'-Dichlorodiphenyldichloroethylene-d8) | 93952-19-3 | p,p'-DDE-d8 is the deuterated form of p,p'-DDE. |
|
V72122 | Paeoniflorgenin (paeoniflorgenin) | 697300-41-7 | Paeoniflorgenin is the deglycosylated metabolite of Paeoniflorin. |
|
V72242 | Perindopril acyl-β-D-glucuronide | 120398-66-5 | Perindopril acyl-β-D-glucuronide is a metabolite of Perindopril. |
|
V72287 | Perphenazine sulfoxide | 10078-25-8 | Perphenazine sulfoxide is the sulfoxide metabolite of Perphenazine, formed by the oxidation of Perphenazine. |
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