A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V53828 | Avenaciolide | 26057-70-5 | Avenaciolide is an antifungal di-γ-lactone found in Aspergillus avenaceus. | |
V53956 | Bac2A TFA | 231306-42-6 | Bac2A TFA is an antimicrobial and immunomodulatory peptide. | |
V5560 | Basifungin | 127785-64-2 | Aureobasidin A (Basifungin) is a cyclic peptide and antifungal antibiotic. | |
V76270 | Benzovindiflupyr | 1072957-71-1 | Benzovindiflupyr is a succinate dehydrogenase inhibitor (SDHI). | |
V53969 | Benzyl 2-hydroxy-6-methoxybenzoate | 24474-71-3 | Benzyl 2-hydroxy-6-methoxybenzoate has strong antifungal effect, with IC50 of 25–26 μg/mL against fungal strains. | |
V4209 | Bifonazole | 60628-96-8 | Bifonazole (Bifomyk;Bay H-4502; Bifokey;Bifon) is a potent imidazole-based antifungal drug with abroad-spectrum of antimycotic activity by interfering with sterol biosynthesis. | |
V53058 | Boscalid | 188425-85-6 | Boscalid is an antifungal compound/agent. | |
V53950 | BTL peptide | 1021461-47-1 | BTL peptide is an antibacterial peptide that has anti-bacterial effect against B. maydis, A. brassicae, A. niger and C. personata. | |
V53914 | Buclosamide | 575-74-6 | Buclosamide is a topical antifungal compound/agent. | |
V52311 | Bulnesol | 22451-73-6 | Bulnesol is a sesquiterpenoid that can be extracted from Salvia miltiorrhiza. | |
V4052 | Caerulomycin A | 21802-37-9 | Caerulomycin A (also known as Cerulomycin, CaeA) is a novel bipyridyl compound that induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. | |
V56261 | Carbendazim-d4 (Carbendazim d4) | 291765-95-2 | Carbendazim-d4 is the deuterated form of Carbendazim. | |
V53996 | Carviolin | 478-35-3 | Carviolin is a compound extracted from the mycelium of the ascomycete Neobulgaria pura. | |
V2511 | Caspofungin Acetate (MK0991) | 179463-17-3 | Caspofungin acetate (formerly known as MK-0991; trade name: Cancidas), a cyclic lipopeptide, is a new class of antifungal drug. | |
V54027 | Cerbinal (gardenaldehyde) | 65597-42-4 | Cerbinal is a natural compound extracted from gardenia. | |
V54018 | Chamaejasmenin D | 865852-47-7 | Chamaejasmenin D is an antimitotic and antifungal compound/agent. | |
V76267 | Chitin synthase inhibitor 10 | 2725075-01-2 | Chitin synthase inhibitor 10 is a chitin synthase (CHS) inhibitor. | |
V76274 | Chitin synthase inhibitor 11 | 2725075-04-5 | Chitin synthase inhibitor 11 is a chitin synthase (CHS) inhibitor. | |
V76263 | Chitin synthase inhibitor 12 | 2725075-05-6 | Chitin synthase inhibitor 12 is a chitin synthase (CHS) inhibitor. | |
V53943 | Chitin synthase inhibitor 13 | 2925228-79-9 | Chitin synthase inhibitor 13 (compound 12g) is a noncompetitive inhibitor of chitin synthase with IC50 of 106.7 μM. |