A family of powerful bioactive lipids known as leukotriene receptors (cys-LTs) act through two structurally distinct G protein-coupled receptors known as the CysLT1 and CysLT2 receptors. Important mediators of human bronchial asthma include the cysteinyl leukotrienes LTC4, LTD4, and LTE4. The second messenger system that the leukotriene receptor uses is phosphatidylinositol-calcium. It belongs to the superfamily of G protein-coupled receptors. When LTD4 activates CysLT1, smooth muscle contracts and grows more, there is oedema, eosinophil migration, and lung mucus layer damage. LTRAs, or leukotriene receptor antagonists, are a class of non-steroidal oral medications. They may also be known as bronchoconstriction preventors with anti-inflammatory properties. LTRAs function by preventing a chemical process that can result in airway inflammation.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V75435 | Zafirlukast-d7 (Zafirlukast d7) | 1217174-18-9 | Zafirlukast-d7 is the deuterated form of Zafirlukast. |
|
V75434 | γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) | 31450-14-3 | γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is an antagonist of leukotriene B receptor 4 (LTB4). |
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