Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.
By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V31055 | Procyanidin B2 | 29106-49-8 | Procyanidin B2 is a naturally occurring flavonoid with anti-tumor, antioxidant and other effects. |
|
V72969 | QD394 | 2132411-21-1 | QD394 is a reactive oxygen species (ROS) inducer that can induce lipid peroxidation, increase the accumulation of intracellular reactive oxygen species, inhibit STAT3 phosphorylation, andcause ferroptosis. |
|
V69228 | Quercetin hydrate | 849061-97-8 | Quercetin hydrate is a naturally occurring flavonoid that activates or inhibits the activity of many proteins. |
|
V72899 | Randialic acid B | 14021-14-8 | Randialic acid B is a triterpenoid and a formyl peptide receptor 1 (FPR1) antagonist. |
|
V72916 | Resorufin-d6 (NSC 12097-d6) | 1196157-65-9 | Resorufin-d6 is the deuterium labelled form of Resorufin. |
|
V78545 | RH-EDA | RH-EDA is a rhodamine-based open fluorescent probe for the detection of hydroxyl radicals in living systems. | |
|
V29430 | Riboflavin Tetrabutyrate | 752-56-7 | Riboflavin Tetrabutyrate is a lipophilic analogue ofRiboflavin(vitamin B2), which is a vitamin B and an important nutrient that plays a key role in maintaining health in humans and other animals. |
|
V72943 | ROS inducer 2 | 2921602-19-7 | ROS inducer 2 (Compound I16) is a reactive oxygen species inducer. |
|
V72937 | ROS inducer 3 | 2921602-09-5 | ROS inducer 3 (Compound I6) is a reactive oxygen species inducer. |
|
V76551 | ROS-ERS inducer 1 | ROS-ERS inducer 1 is a type II ICD (immunogenic cell death) inducer. | |
|
V81324 | ROS-IN-2 | ROS-IN-2 (compound 85) is a hypolupine triterpene analogue. | |
|
V72930 | Rucosopasem manganese (GC4711) | 2248030-85-3 | Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. |
|
V76535 | Salpyran dihydrochloride | Salpyran di-HCl is a copper(II) selective chelator with research potential. | |
|
V72901 | Salvianolic acid Y | 1638738-76-7 | Salvianolic acid Y is a phenolic acid with the same planar structure as Salvianolic acid B. |
|
V72912 | Sanguinarine (gluconate) (Sanguinarin (gluconate); Sanguinarium (gluconate); Pseudochelerythrine (gluconate)) | 132210-34-5 | Sanguinarine (Sanguinarin) gluconate is an alkaloid derived from Sanguinaria Canadensis that stimulates apoptosis by activating the production of reactive oxygen species (ROS). |
|
V72956 | Shatavarin IV (Asparanin B) | 84633-34-1 | Shatavarin IV is a steroidal saponin extracted from the roots of Asparagus racemosus (Lilyaceae). |
|
V70223 | SMTIN-T140 | 2851532-40-4 | SMTIN-T140 (compound 6a) is a potent TRAP1 (tumor necrosis factor receptor-associated protein 1) inhibitor (antagonist) with IC50 of 1.646 μM. |
|
V28673 | Sodium formononetin-3'-sulfonate | 949021-68-5 | Sodium formononetin-3'-sulfonate (Sul-F) is a water-soluble (H2O-soluble) analogue of formononetin. |
|
V72895 | Sonlicromanol hydrochloride (KH176 hydrochloride) | 2162149-24-6 | Sonlicromanol (KH176) HCl is an analogue of Trolox and a ROS-redox modulator that can penetrate the BBB (blood-brain barrier). |
|
V72902 | Spiraeoside (Quercetin 4′-O-glucoside) | 20229-56-5 | Spiraeoside is an orally bioactive naturally occurring compound that displays anti-oxidant effect, inhibiting the generation of reactive oxygen species and malondialdehyde. |
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