Reactive Oxygen Species

Reactive Oxygen Species

Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.

By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.

Reactive Oxygen Species related products

Structure Cat No. Product Name CAS No. Product Description
V72891 N-trans-Caffeoyltyramine 103188-48-3 N-trans-Caffeoyltyramine is a potent inflammatory response modulator with anti-oxidant effect and anticoagulant effects.
V31815 Neohesperidin dihydrochalcone 20702-77-6 Neohesperidin dihydrochalcone (Neohesperidin DC; NHDC),an artificial sweetener and a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.
V71491 Nisoldipine-d4 (Nisoldipine d4) 1219795-47-7 Nisoldipine-d4 is the deuterium labelled form of Nisoldipine.
V71539 Nisoldipine-d6 (BAY-k 5552-d6) 1285910-03-3 Nisoldipine-d6 is the deuterium labelled form of Nisoldipine.
V71501 Nisoldipine-d7 (Nisoldipine d7) 1189718-34-0 Nisoldipine-d7 is the deuterated substitute of Nisoldipine.
V2422 Norbergenin 79595-97-4 Norbergenin is an ortho-desmethyl analogue of bergenin with moderate anti-oxidant effect (IC50 for scavenging DPPH free radicals is 13 μM; scavenging superoxide anion is 32 μM).
V69814 Nrf2/HO-1 activator 1 2883506-60-1 Nrf2/HO-1 activator 1 (Compound 24) is a potent Nrf2/HO-1 activator and neuro-protection agent.
V26811 OBA-09 856095-68-6 OBA-09 (OBA09) is a novel and potent neuroprotective agent.
V72938 Octapeptide-2 1374396-34-5 Octapeptide-2 is a biologically active peptide with hair growth-promoting effects that has been reported as an ingredient of cosmetics.
V72911 OPC-163493 1644467-84-4 OPC-163493 is an orally bioactive, liver-targeted mitochondrial uncoupler.
V72948 Palmitoyl tripeptide-38 1447824-23-8 Palmitoyl tripeptide-38 is a biologically active peptide with anti-aging activities.
V72926 Pelargonidin 3,5-diglucoside chloride 17334-58-6 elargonidin 3,5-diglucoside (chloride) is a natural pigment found in large amounts in red fruits and vegetables.
V72966 Pennogenin 507-89-1 Pennogenin is a naturally occurring compound found in the rhizome of Tibetan Trillium.
V30439 Phillygenin 487-39-8 Phillygenin(Phillygenol,Phillygenol;Epipinoresinol methyl ether,Sylvatesmin,Forsythigenol) is a naturally occurringa bioactive intergradient isolated from Osmanthus fragrans, showing diverse bioactivities such as anti-inflammatory, anti-obesity and antipyretic activities.
V7963 Photochlor (HTTP) 149402-51-7 Photochlor (HTTP),a photodynamic therapy (PDT) agent, is a lipophilic, second-generation, chlorin-based photosensitizer.
V72968 Photosensitizer-1 1886-13-1 Photosensitizer-1 (Compound CLB-13) is a photosensitizer.
V72964 Photosensitizer-1 hydrochloride 2771189-66-1 Photosensitizer-1 (Compound CLB-13) HCl is a photosensitizer.
V72886 Phycocyanobilin (phycocyanin; phycocyanin) 20298-86-6 Phycocyanobilin is an orally bioactive antioxidant (reactive oxygen species) and an effective reactive oxygen species scavenger.
V72974 Piperkadsin A 895543-36-9 Piperkadsin A is a potent ROS inhibitor.
V34664 PK11007 874146-69-7 PK11007 is a novel and potent anti-p53 compound with anti-tumor activities through activation of unstablep53 (tumor suppressor p53).
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