A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V76277 | Pyrisoxazole (SYP-Z048) | 847749-37-5 | Pyrisoxazole (SYP-Z048) is a fungicide. |
|
V35009 | Pyromeconic acid | 496-63-9 | Pyromeconic acid is an antifungal substance. |
|
V76269 | Quellenin | 2243042-31-9 | Quellenin is an anti-Saprolegnia compound. |
|
V34293 | Quercetin 7-rhamnoside | 22007-72-3 | Vincetoxicoside B has antifungal activity. |
|
V53995 | Rabdoserrin A | 96685-01-7 | Rabdoserrin A is a diterpenoid with antifungal activity. |
|
V3506 | Ravuconazole | 182760-06-1 | Ravuconazole (formerly known as BMS-207147 and ER-30346) is a novel, orally bioavailable and potent triazole antifungal agent with a broad spectrum of potent activity against a wide range of fungi. |
|
V56173 | Ravuconazole-d4 (Ravuconazole d4) | 1329499-27-5 | Ravuconazole-d4 is the deuterated form of Ravuconazole. |
|
V53065 | Rolusafine | 2089153-78-4 | Rolusafine is an antifungal compound/agent. |
|
V36744 | S-F24 | 2946669-78-7 | S-F24 is an antifungal agent (fungal) with good broad spectrum. |
|
V5297 | Salifungin (Bromosalicylchloranilide; Multifungin) | 3679-64-9 | Salifungin (also known as Bromochlorosalicylanilide; Multifungin) is a novel and potent antifungal agent and may cause allergic contact dermatitis in some individuals. |
|
V2081 | Sapogenins Glycosides | 8047-15-2 | Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L. |
|
V80160 | SDH-IN-10 | SDH-IN-10 is a potent succinate dehydrogenase inhibitor (SDHI) with antifungal effects. | |
|
V84554 | SDH-IN-11 | 2998946-58-8 | |
|
V83396 | SDH-IN-12 | 3027210-28-9 | |
|
V37131 | SDH-IN-3 | 2805297-11-2 | SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor (antagonist) with IC50 of 7.6 μg/mL. |
|
V81378 | SDH-IN-4 | SDH-IN-4 (compound B6) is a succinate dehydrogenase (SDH) inhibitor (antagonist) with IC50 of 0.28 μg/mL. | |
|
V53990 | SDH-IN-5 | 2922765-95-3 | SDH-IN-5 (compound 7d) is a potent inhibitor of succinate dehydrogenase (SDH) with IC50 of 3.293 μM. |
|
V81379 | SDH-IN-6 | SDH-IN-6 (compound 6i) is a potent succinate dehydrogenase (SDH) inhibitor. | |
|
V81380 | SDH-IN-7 | SDH-IN-7 (compound G28) is a potent succinate dehydrogenase (SDH) inhibitor (antagonist) with IC50 of 26 nM against porcine SDH. | |
|
V80021 | SDH-IN-8 | SDH-IN-8 (compound G40) is a potent succinate dehydrogenase (SDH) inhibitor (antagonist) with IC50 of 27 nM against porcine SDH. |
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