The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V71513 | Menthol-d4 | 1217765-02-0 | Menthol-d4 is the deuterium labelled form of Menthol. | |
V33725 | Mibefradil dihydrochloride | 116666-63-8 | Mibefradil dihydrochloride (Ro 40-5967; trade name: Posicor), thedihydrochloride salt of miberfradil, is a CCB/calcium channel blocker with anti-hypertensive activity. | |
V71538 | MMK1 | 271246-66-3 | MMK1 is a potent and specific human formyl peptide receptor-like 1 (FPRL-1/FPR2) agonist/activator with EC50s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. | |
V80794 | MMK1 TFA | MMK1 TFA is a potent and specific human formyl peptide receptor-like 1 (FPRL-1/FPR2) agonist/activator with EC50s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. | ||
V80860 | Myoregulin (MLN peptide) | Myoregulin (MLN peptide) is a member of the regulin family. | ||
V80861 | Myoregulin TFA (MLN peptide TFA) | Myoregulin (MLN peptide) TFA is a member of the regulin family. | ||
V80865 | Myr-TAT-CBD3 | Myr-TAT-CBD3 is a CRMP2-CaV2.2 interaction inhibitor. | ||
V71516 | N-Desalkylflurazepam (Norfludiazepam) | 2886-65-9 | N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepines such as Flurazepam. | |
V71536 | Ned-K | 2250019-90-8 | Ned-K is a niacin adenine dinucleotide phosphate (NAADP) antagonist. | |
V71508 | Nemadipine-A | 54280-71-6 | Nemadipine-A is a specific inhibitor of the EGL-19 Ca2+ channel. | |
V71505 | Norverapamil-d7 hydrochloride ((±)-Norverapamil-d7 (hydrochloride); D591-d7 (hydrochloride)) | 1216413-74-9 | Norverapamil-d7 ( HCl) is a deuterium labelled form of Norverapamil. | |
V76662 | PACAP-38 (31-38), human, mouse, rat TFA | PACAP-38 (31-38), human, mouse, rat TFA is a PAC1 receptor agonist/activator. | ||
V81035 | Palmitoylglycine-d31 (N-palmitoylglycine-d31) | Palmitoylglycine-d31 is the deuterated form of Palmitoylglycine. | ||
V80048 | PptT-IN-4 | PptT-IN-4 (Compound 3a) is a PptT inhibitor (IC50= 0.71 μM). | ||
V81217 | Propiverine-d7 hydrochloride (propiverine d7 hydrochloride) | Propiverine-d7 ( HCl) is the deuterated form of Propiverine HCl. | ||
V71490 | ProTx-I | 484598-35-8 | ProTx-I, a toxin derived from Thrixopelma pruriens, is a potent and specific CaV3.1 channel blocker with IC50s of 0.2 μM and 31.8 μM for hCAV3.1 and hCaV3.2, respectively. | |
V71485 | Ranolazine-d3 (ranolazine d3) | 1054624-77-9 | Ranolazine-d3 is the deuterated form of Ranolazine. | |
V71506 | Rp-8-Br-cGMPS sodium salt (Rp-8-bromo-Cyclic GMPS sodium salt) | 208445-06-1 | Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is an effective Ca2+-ATPase activator. | |
V71469 | Ruthenium red (Ruthenium red; Ammoniated ruthenium oxychloride) | 11103-72-3 | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye extensively used for observation of cells, tissues and vegetative bacteria under electron microscopy (EM). | |
V78416 | RyR2 stabilizer-1 | RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC50s of 2.7 μM and 383 nM for RyR2 and SERCA2, respectively. |