Ligands for Target Protein for PROTAC

Target proteins are often proteins that may contribute significantly to the development of illnesses through overexpression or accumulation. Numerous PROTACs have been created to destroy kinases (like MEK, KRAS, CDK, and Bcr/Abl), transcription factors (like p53, STAT, RAR, ER, and AR), epigenetic tools (like HDAC and BET bromodomain), and E3 ligases themselves (like MDM2).

Target proteins are often proteins that may contribute significantly to the progression of illnesses through overexpression or accumulation. Numerous PROTACs have been created to destroy E3 ligases including MDM2, MEK, KRAS, CDK, and Bcr/Abl, transcription factors like p53, STAT, RAR, ER, and AR, epigenetic tools like HDAC, and BET bromodomain.

Ligands for Target Protein for PROTAC related products

Cat No.	Product Name	CAS No.	Product Description
V88229	DENV ligand 1	1628758-48-4	DENV ligand 1 is a ligand for DENV E protein.
V88228	DENV ligand 2		DENV ligand 2 is a ligand for DENV E protein.
V94129	DHHC3 degrader 1		DHHC3 degrader 1 is a PROTAC target protein ligand that can be used to synthesize PCC16 chloride.
V99945	diABZI-V/C-Mal	3035557-55-9	diABZI-V/C-Mal is a PROTAC target protein ligand.
V51749	Dimethyl-F-OICR-9429-COOH	2407458-49-3	Dimethyl-F-OICR-9429-COOH is a ligand for the target protein WD40 repeat domain protein 5 (WDR5) and can be used for the synthesis of PROTAC.
V82613	Dimethylamino-PEG3	2741-30-2	Dimethylamino-PEG3 is a PROTAC (PROteolysis TArgeting Chimera) linker of the Polyethylene glycol (PEG) category, may be utilized to prepare PROTAC protein degraders.
V105584	dTAG Targeting Ligand 1	755039-56-6	dTAG Targeting Ligand 1 (SUBSTITUTE SHEET 245) is a PROTAC target protein ligand (PROTAC target protein ligand).
V2592	DUPA	302941-52-2	DUPA is a glutamate urea that serves as a targeting moiety in a bioactive molecule conjugate for the selective and targeted delivery of cytotoxic drugs to prostate cancer/tumor cells.
V93699	DYR530	2410298-39-2	DYR530 is a ligand for the PROTAC target protein (protein kinase DYRK1A).
V93858	DYR684m		DYR530-Boc is a target protein ligand activity control that can be used in the synthesis of PROTACs.
V87951	DYRK2 ligand 1		DYRK2 ligand 1 is the target protein ligand of PROTAC DYRK2 degrader 1.
V104970	EA-89		EA-89 is a potent and selective BRD9 inhibitor with anti-tumor activity.
V104972	EA-89-Succinic acid		EA-89-succinic acid (Compound 26) is an active control of the target protein ligand EA-89 and can be used for synthetic PROTAC-related research.
V104285	EGFR ligand-11	2550394-08-4	EGFR ligand-11 is the target protein ligand of EGFR and can be used to synthesize PROTAC MS154.
V97292	EP300/CBP ligand 1		EP300/CBP ligand 1 is a PROTAC target protein ligand (target protein ligand of PROTACs).
V104259	ER ligand-2		ER ligand-2 (the target protein ligand of compound 24) is a ligand for ER.
V104911	ER ligand-3		ER ligand-3 is the target protein ligand of PROTAC.
V104016	ER ligand-4		ER ligand-4 (compound 45a) is the PROTAC target protein ligand of ERD-12310A.
V104987	ER ligand-5	2421262-07-7	ER ligand-5 is a ligand for the estrogen receptor and can be used as a target protein ligand to synthesize the PROTAC degrader ERα Degrader-10.
V104989	ER ligand-6	2504914-79-6	ER ligand-6 is the target protein ligand of PROTAC ER Degrader-14.