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Structure Cat No. Product Name CAS No. Product description
V0300 Olaparib (AZD2281; KU0059436) 763113-22-0 Olaparib (formerly also known as AZD-2281; KU-59436; KU0059436; trade name Lynparza) is a potent,novel and orally bioavailable small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential anticancer activity.
V32889 DPN 1428-67-7 DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor ERβ selective ligand with EC50 of 0.85 nM.
V0503 Apatinib (Rivoceranib, YN968D1) 811803-05-1 Apatinib (formerly known as Rivoceranib,YN-968D1) is a potent, orally bioavailable, and selective inhibitor of the VEGF (vascular endothelial growth factor receptor) signaling pathway withpotential antiangiogenic and antineoplastic activities.
V19288 DCKA 131123-76-7 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective NMDA receptor glycine site competitive antagonist (inhibitor) with a Kb of 65 nM.
V47750 15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid 1039673-32-9 15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound extracted from Chloranthus spicatus.
V30349 Echinocystic acid 510-30-5 Echinocystic acid is a naturally occurringpentacyclic triterpene found in the fruits of Gleditsia sinensis Lam with antioxidant, anti-inflammatory and anticancer pactivities.
V20571 Enmenol 28957-06-4 Enmenol is a novel and potent bioactive compound
V0342 Tofacitinib (CP690550; tasocitinib) 477600-75-2 Tofacitinib (also known as tasocitinib or CP-690550, sold under the brandXeljanz),is a novel and potent inhibitor of JAK3 (Janus-Associated kinase) with potential anti-inflammatory activity.
V52787 Carbazole-d8 (咔唑-d8) 38537-24-5 Carbazole-d8 is the deuterated form of Carbazole (HY-D0204).
V0075 AZD1390 2089288-03-7 AZD1390 (AZD-1390) is a novel, potent, selective, first-in-class orally bioavailable and CNS penetrant inhibitor of Ataxia-telangiectasia mutated (ATM) kinase with potential anticancer activity.
V35046 Ditiocarb (Diethyldithiocarbamic acid) 147-84-2 Ditiocarb (Diethyldithiocarbamic acid) is a copper reagent that reacts with Cu2+ solution to form a complex, which increases the copper replacement precipitation rate.
V0284 Sodium Phenylbutyrate (4-PBA sodium) 1716-12-7 Sodium phenylbutyrate (4-Phenylbutyric acid sodium; 4-PBA sodium),an orphan drug marketed by Ucyclyd Pharma, is a novel and potent histone deacetylase (HDAC) inhibitor used as an as adjunctive therapy for chronic treatment of urea cycle disorders involving deficiencies of argininosuccinic acid synthetase (AS), ornithine transcarbamylase (OTC), or carbamylphosphate synthetase (CPS).
V0024 Belnacasan (VX765) 273404-37-8 Belnacasan (also known as VX-765) is a novel, potent, selective and orally bioactive prodrug of VRT-043198 which is a potent and selective inhibitor of caspase-1 withKi values of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively.
V0174 Rapamycin (Sirolimus; AY22989) 53123-88-9 Rapamycin (also known as Sirolimus; AY-22989), a natural macrocyclic lactone isolated from the bacterium Streptomyces hygroscopicus, is a specific and potent mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.
V0725 Telaprevir ( LY-570310; VX950; MP-424) 402957-28-2 Telaprevir (also known as LY570310; VX-950; MP424; trade names: Incivek; Incivo), a marketed medication for HCV treatment, is a selective, and reversible peptidomimetic inhibitor of HCV NS3-4A serine protease with an IC50 of 0.35 μM.
V0522 Semaxanib (SU-5416) 204005-46-9 Semaxanib (also known as SU5416) is a novel, potent and selective VEGFR (Flk-1/KDR) inhibitor with potential anticancer activity.
V0630 Pexidartinib (PLX3397; Turalio; CML261; FP113) 1029044-16-3 Pexidartinib (formerly PLX-3397; CML-261;FP-113; trade name Turalio) is an orally bioavailable and multi-targeted RTK (receptor tyrosine kinase) inhibitor of CSF-1R, Kit, and Flt3 with potential antineoplastic activity.
V0633 GW2580 (SC203877) 870483-87-7 GW2580 (also known as SC-203877)is a novel, potent, selective, and orally bioavailable c-Fms kinaseCSF-1R inhibitor with potential antineoplastic activity.
V0493 Foretinib (GSK-1363089; XL-880; EXEL2880; GSK-089) 849217-64-7 Foretinib (also known as GSK1363089; XL880; EXEL-2880; GSK089) is a novel, potent, ATP-competitive small-molecule inhibitor of multipletyrosine kinases (e.
V0245 Acadesine (AICAR; NSC-105823) 2627-69-2 Acadesine (also known as NSC105823,AICA-riboside, and AICAR) is a novel and potent AMPK (AMP-activated protein kinase) activatorwith potential antitumor and antidiabetic activity.
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