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Structure Cat No. Product Name CAS No. Product description
V0725 Telaprevir ( LY-570310; VX950; MP-424) 402957-28-2 Telaprevir (also known as LY570310; VX-950; MP424; trade names: Incivek; Incivo), a marketed medication for HCV treatment, is a selective, and reversible peptidomimetic inhibitor of HCV NS3-4A serine protease with an IC50 of 0.35 μM.
V19288 DCKA 131123-76-7 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective NMDA receptor glycine site competitive antagonist (inhibitor) with a Kb of 65 nM.
V0630 Pexidartinib (PLX3397; Turalio; CML261; FP113) 1029044-16-3 Pexidartinib (formerly PLX-3397; CML-261;FP-113; trade name Turalio) is an orally bioavailable and multi-targeted RTK (receptor tyrosine kinase) inhibitor of CSF-1R, Kit, and Flt3 with potential antineoplastic activity.
V0522 Semaxanib (SU-5416) 204005-46-9 Semaxanib (also known as SU5416) is a novel, potent and selective VEGFR (Flk-1/KDR) inhibitor with potential anticancer activity.
V0415 Apabetalone (RVX-08, RVX-000222) 1044870-39-4 Apabetalone (also known as RVX-208, RVX000222) is a novel and potent inhibitor of BET (Bromodomain and Extra-Terminal) bromodomain (BD) with potential anti-inflammatory activity and the potential to be used in the treatment of cardiovascular diseases.
V39377 DBCO-PEG3-TCO DBCO-PEG3-TCO is a non-cleavable (non-degradable) ADC linker containing 3 Polyethylene glycol (PEG) units, which may be utilized to prepare Antibody-drug conjugates (ADC).
V32889 DPN 1428-67-7 DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor ERβ selective ligand with EC50 of 0.85 nM.
V47750 15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid 1039673-32-9 15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound extracted from Chloranthus spicatus.
V30349 Echinocystic acid 510-30-5 Echinocystic acid is a naturally occurringpentacyclic triterpene found in the fruits of Gleditsia sinensis Lam with antioxidant, anti-inflammatory and anticancer pactivities.
V20571 Enmenol 28957-06-4 Enmenol is a novel and potent bioactive compound
V0342 Tofacitinib (CP690550; tasocitinib) 477600-75-2 Tofacitinib (also known as tasocitinib or CP-690550, sold under the brandXeljanz),is a novel and potent inhibitor of JAK3 (Janus-Associated kinase) with potential anti-inflammatory activity.
V0390 EPZ015666 (GSK3235025) 1616391-65-1 EPZ015666 (GSK-3235025), an analog ofEPZ-015866, is a potent, selective and orally bioavailable inhibitor of PRMT5 (protein arginine methyltransferase) with antineoplastic activity.
V52787 Carbazole-d8 (咔唑-d8) 38537-24-5 Carbazole-d8 is the deuterated form of Carbazole (HY-D0204).
V35046 Ditiocarb (Diethyldithiocarbamic acid) 147-84-2 Ditiocarb (Diethyldithiocarbamic acid) is a copper reagent that reacts with Cu2+ solution to form a complex, which increases the copper replacement precipitation rate.
V0245 Acadesine (AICAR; NSC-105823) 2627-69-2 Acadesine (also known as NSC105823,AICA-riboside, and AICAR) is a novel and potent AMPK (AMP-activated protein kinase) activatorwith potential antitumor and antidiabetic activity.
V0729 Ritonavir (ABT-538; Norvir) 155213-67-5 Ritonavir (previously known as ABT-538; A-84538; RTV; ABT538, trade name: Norvir) is a L-valine derivative and potent inhibitor of HIV-1 protease used to treat HIV infection and AIDS. It is widely used as a booster for other protease inhibitors/PIs such as lopinavir, and makes them work better.
V0633 GW2580 (SC203877) 870483-87-7 GW2580 (also known as SC-203877)is a novel, potent, selective, and orally bioavailable c-Fms kinaseCSF-1R inhibitor with potential antineoplastic activity.
V0572 Imatinib Mesylate (STI571; Gleevec; Glivec) 220127-57-1 Imatinib Mesylate (also known as STI571 mesylate; trade names: Gleevec or Glivec), the mesylate salt of imatinib, is an orally bioavailable,potent,multi-kinase inhibitor of v-Abl, c-Kit and PDGFR with potential antitumor activity.
V2967 PF-05089771 1235403-62-9 PF-05089771 (PF05089771) is a potent and subtype selective NaV1.7 inhibitor (IC50 = 11 nM) and Nav1.8voltage-gated sodium channelblocker with the potential to be used in the treatment of chronic neuropathic pain.
V0035 Pomalidomide (CC4047 or actimid) 19171-19-8 Pomalidomide (formerly also known as CC-4047 or actimid), an analog of thalidomide, is a potent andorally bioavailable immunomodulatory molecule with antineoplastic activity.
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