|
V0300
|
Olaparib (AZD2281; KU0059436) |
763113-22-0 |
Olaparib (formerly also known as AZD-2281; KU-59436; KU0059436; trade name Lynparza) is a potent,novel and orally bioavailable small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential anticancer activity. |
|
V32889
|
DPN |
1428-67-7 |
DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor ERβ selective ligand with EC50 of 0.85 nM. |
|
V0503
|
Apatinib (Rivoceranib, YN968D1) |
811803-05-1 |
Apatinib (formerly known as Rivoceranib,YN-968D1) is a potent, orally bioavailable, and selective inhibitor of the VEGF (vascular endothelial growth factor receptor) signaling pathway withpotential antiangiogenic and antineoplastic activities. |
|
V19288
|
DCKA |
131123-76-7 |
5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective NMDA receptor glycine site competitive antagonist (inhibitor) with a Kb of 65 nM. |
|
V47750
|
15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid |
1039673-32-9 |
15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound extracted from Chloranthus spicatus. |
|
V30349
|
Echinocystic acid |
510-30-5 |
Echinocystic acid is a naturally occurringpentacyclic triterpene found in the fruits of Gleditsia sinensis Lam with antioxidant, anti-inflammatory and anticancer pactivities. |
|
V20571
|
Enmenol |
28957-06-4 |
Enmenol is a novel and potent bioactive compound |
|
V0342
|
Tofacitinib (CP690550; tasocitinib) |
477600-75-2 |
Tofacitinib (also known as tasocitinib or CP-690550, sold under the brandXeljanz),is a novel and potent inhibitor of JAK3 (Janus-Associated kinase) with potential anti-inflammatory activity. |
|
V52787
|
Carbazole-d8 (咔唑-d8) |
38537-24-5 |
Carbazole-d8 is the deuterated form of Carbazole (HY-D0204). |
|
V0075
|
AZD1390 |
2089288-03-7 |
AZD1390 (AZD-1390) is a novel, potent, selective, first-in-class orally bioavailable and CNS penetrant inhibitor of Ataxia-telangiectasia mutated (ATM) kinase with potential anticancer activity. |
|
V35046
|
Ditiocarb (Diethyldithiocarbamic acid) |
147-84-2 |
Ditiocarb (Diethyldithiocarbamic acid) is a copper reagent that reacts with Cu2+ solution to form a complex, which increases the copper replacement precipitation rate. |
|
V0284
|
Sodium Phenylbutyrate (4-PBA sodium) |
1716-12-7 |
Sodium phenylbutyrate (4-Phenylbutyric acid sodium; 4-PBA sodium),an orphan drug marketed by Ucyclyd Pharma, is a novel and potent histone deacetylase (HDAC) inhibitor used as an as adjunctive therapy for chronic treatment of urea cycle disorders involving deficiencies of argininosuccinic acid synthetase (AS), ornithine transcarbamylase (OTC), or carbamylphosphate synthetase (CPS). |
|
V0024
|
Belnacasan (VX765) |
273404-37-8 |
Belnacasan (also known as VX-765) is a novel, potent, selective and orally bioactive prodrug of VRT-043198 which is a potent and selective inhibitor of caspase-1 withKi values of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. |
|
V0174
|
Rapamycin (Sirolimus; AY22989) |
53123-88-9 |
Rapamycin (also known as Sirolimus; AY-22989), a natural macrocyclic lactone isolated from the bacterium Streptomyces hygroscopicus, is a specific and potent mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells. |
|
V0725
|
Telaprevir ( LY-570310; VX950; MP-424) |
402957-28-2 |
Telaprevir (also known as LY570310; VX-950; MP424; trade names: Incivek; Incivo), a marketed medication for HCV treatment, is a selective, and reversible peptidomimetic inhibitor of HCV NS3-4A serine protease with an IC50 of 0.35 μM. |
|
V0522
|
Semaxanib (SU-5416) |
204005-46-9 |
Semaxanib (also known as SU5416) is a novel, potent and selective VEGFR (Flk-1/KDR) inhibitor with potential anticancer activity. |
|
V0630
|
Pexidartinib (PLX3397; Turalio; CML261; FP113) |
1029044-16-3 |
Pexidartinib (formerly PLX-3397; CML-261;FP-113; trade name Turalio) is an orally bioavailable and multi-targeted RTK (receptor tyrosine kinase) inhibitor of CSF-1R, Kit, and Flt3 with potential antineoplastic activity. |
|
V0633
|
GW2580 (SC203877) |
870483-87-7 |
GW2580 (also known as SC-203877)is a novel, potent, selective, and orally bioavailable c-Fms kinaseCSF-1R inhibitor with potential antineoplastic activity. |
|
V0493
|
Foretinib (GSK-1363089; XL-880; EXEL2880; GSK-089) |
849217-64-7 |
Foretinib (also known as GSK1363089; XL880; EXEL-2880; GSK089) is a novel, potent, ATP-competitive small-molecule inhibitor of multipletyrosine kinases (e. |
|
V0245
|
Acadesine (AICAR; NSC-105823) |
2627-69-2 |
Acadesine (also known as NSC105823,AICA-riboside, and AICAR) is a novel and potent AMPK (AMP-activated protein kinase) activatorwith potential antitumor and antidiabetic activity. |