|
V0725
|
Telaprevir ( LY-570310; VX950; MP-424) |
402957-28-2 |
Telaprevir (also known as LY570310; VX-950; MP424; trade names: Incivek; Incivo), a marketed medication for HCV treatment, is a selective, and reversible peptidomimetic inhibitor of HCV NS3-4A serine protease with an IC50 of 0.35 μM. |
|
V19288
|
DCKA |
131123-76-7 |
5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective NMDA receptor glycine site competitive antagonist (inhibitor) with a Kb of 65 nM. |
|
V0630
|
Pexidartinib (PLX3397; Turalio; CML261; FP113) |
1029044-16-3 |
Pexidartinib (formerly PLX-3397; CML-261;FP-113; trade name Turalio) is an orally bioavailable and multi-targeted RTK (receptor tyrosine kinase) inhibitor of CSF-1R, Kit, and Flt3 with potential antineoplastic activity. |
|
V0522
|
Semaxanib (SU-5416) |
204005-46-9 |
Semaxanib (also known as SU5416) is a novel, potent and selective VEGFR (Flk-1/KDR) inhibitor with potential anticancer activity. |
|
V0415
|
Apabetalone (RVX-08, RVX-000222) |
1044870-39-4 |
Apabetalone (also known as RVX-208, RVX000222) is a novel and potent inhibitor of BET (Bromodomain and Extra-Terminal) bromodomain (BD) with potential anti-inflammatory activity and the potential to be used in the treatment of cardiovascular diseases. |
|
V39377
|
DBCO-PEG3-TCO |
|
DBCO-PEG3-TCO is a non-cleavable (non-degradable) ADC linker containing 3 Polyethylene glycol (PEG) units, which may be utilized to prepare Antibody-drug conjugates (ADC). |
|
V32889
|
DPN |
1428-67-7 |
DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor ERβ selective ligand with EC50 of 0.85 nM. |
|
V47750
|
15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid |
1039673-32-9 |
15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound extracted from Chloranthus spicatus. |
|
V30349
|
Echinocystic acid |
510-30-5 |
Echinocystic acid is a naturally occurringpentacyclic triterpene found in the fruits of Gleditsia sinensis Lam with antioxidant, anti-inflammatory and anticancer pactivities. |
|
V20571
|
Enmenol |
28957-06-4 |
Enmenol is a novel and potent bioactive compound |
|
V0342
|
Tofacitinib (CP690550; tasocitinib) |
477600-75-2 |
Tofacitinib (also known as tasocitinib or CP-690550, sold under the brandXeljanz),is a novel and potent inhibitor of JAK3 (Janus-Associated kinase) with potential anti-inflammatory activity. |
|
V0390
|
EPZ015666 (GSK3235025) |
1616391-65-1 |
EPZ015666 (GSK-3235025), an analog ofEPZ-015866, is a potent, selective and orally bioavailable inhibitor of PRMT5 (protein arginine methyltransferase) with antineoplastic activity. |
|
V52787
|
Carbazole-d8 (咔唑-d8) |
38537-24-5 |
Carbazole-d8 is the deuterated form of Carbazole (HY-D0204). |
|
V35046
|
Ditiocarb (Diethyldithiocarbamic acid) |
147-84-2 |
Ditiocarb (Diethyldithiocarbamic acid) is a copper reagent that reacts with Cu2+ solution to form a complex, which increases the copper replacement precipitation rate. |
|
V0245
|
Acadesine (AICAR; NSC-105823) |
2627-69-2 |
Acadesine (also known as NSC105823,AICA-riboside, and AICAR) is a novel and potent AMPK (AMP-activated protein kinase) activatorwith potential antitumor and antidiabetic activity. |
|
V0729
|
Ritonavir (ABT-538; Norvir) |
155213-67-5 |
Ritonavir (previously known as ABT-538; A-84538; RTV; ABT538, trade name: Norvir) is a L-valine derivative and potent inhibitor of HIV-1 protease used to treat HIV infection and AIDS. It is widely used as a booster for other protease inhibitors/PIs such as lopinavir, and makes them work better. |
|
V0633
|
GW2580 (SC203877) |
870483-87-7 |
GW2580 (also known as SC-203877)is a novel, potent, selective, and orally bioavailable c-Fms kinaseCSF-1R inhibitor with potential antineoplastic activity. |
|
V0572
|
Imatinib Mesylate (STI571; Gleevec; Glivec) |
220127-57-1 |
Imatinib Mesylate (also known as STI571 mesylate; trade names: Gleevec or Glivec), the mesylate salt of imatinib, is an orally bioavailable,potent,multi-kinase inhibitor of v-Abl, c-Kit and PDGFR with potential antitumor activity. |
|
V2967
|
PF-05089771 |
1235403-62-9 |
PF-05089771 (PF05089771) is a potent and subtype selective NaV1.7 inhibitor (IC50 = 11 nM) and Nav1.8voltage-gated sodium channelblocker with the potential to be used in the treatment of chronic neuropathic pain. |
|
V0035
|
Pomalidomide (CC4047 or actimid) |
19171-19-8 |
Pomalidomide (formerly also known as CC-4047 or actimid), an analog of thalidomide, is a potent andorally bioavailable immunomodulatory molecule with antineoplastic activity. |