| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
| ln Vitro |
The purpose of this study was to evaluate the combined effects of sodium chloride (NaCl) substitutes, including potassium lactate (K-lactate) and calcium ascorbate (Ca-ascorbate), on the physicochemical and sensory characteristics of low-sodium frankfurter sausage (1.2% content of NaCl). Sausages produced with 40% substitution of NaCl with combined K-lactate and Ca-ascorbate showed a higher value of lightness (P<0.001) than sausages containing 2.0% content of NaCl (control). However, the sensory panels were unable to distinguish a difference in color intensity between the control and treatment groups. Frankfurter sausages produced with 30% K-lactate and 10% Ca-ascorbate exhibited similar water-holding capacity, textural properties, and organoleptic characteristics (P>0.05) when compared to control sausages. Thus, the use of these salt mixtures is a good way to reduce the NaCl content in meat products while maintaining the quality of meat products. These results may be useful in developing low-sodium meat products.[1]
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| ln Vivo |
Frankfurter-type sausages were prepared with potassium lactate, sodium diacetate and various levels of a mixture of potassium lactate and sodium diacetate. The development of Lactobacillus sake and Listeria monocytogenes and the sensory quality were compared with a reference product without any of these additions. It was shown that addition of 2–3% of a solution, containing a mixture of 56% potassium lactate and 4% sodium diacetate to Frankfurter-type sausages inhibited the development of L. sake and L. monocytogenes bacteria inoculated on to the product during storage at 4°C. L. sake bacteria were mainly inhibited by the addition of lactates and its water activity lowering effect, resulting in a shelf-life extension with 75–125%. In Frankfurter sausage with 0.1% sodium diacetate L. sake was not inhibited, but the development of L. monocytogenes was retarded. The increase of L. monocytogenes also slowed down when L. sake numbers reached 108 cfu g−1, probably as a result of lactic acid and/or bacteriocins production in those products. A synergistic effect of the combined addition of lactate and diacetate was observed at the end of the shelf-life, where L. monocytogenes was inhibited in Frankfurters with mixtures of potassium lactate and sodium diacetate while some growth was observed in products only containing potassium lactate. Sensory properties of the product were not significantly influenced by the addition of 2–3% of solutions containing a potassium lactate/sodium diacetate mixture.[2]
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| References |
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| Additional Infomation |
Sources/Uses
Used as a flavor enhancer; Used in solution as an antioxidant and synergist |
| Molecular Formula |
C3H5KO3
|
|---|---|
| Molecular Weight |
128.17
|
| Exact Mass |
127.987
|
| CAS # |
996-31-6
|
| Related CAS # |
Lactate;50-21-5;Lactate calcium;814-80-2;Lactate sodium;72-17-3
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| PubChem CID |
23671663
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| Appearance |
Colorless to light yellow liquid
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| Density |
1.316 g/ml (predict)
|
| Boiling Point |
227.6ºC at 760 mmHg
|
| Flash Point |
109.9ºC
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| Hydrogen Bond Donor Count |
1
|
| Hydrogen Bond Acceptor Count |
3
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
7
|
| Complexity |
63.2
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
CC(C(=O)[O-])O.[K+]
|
| InChi Key |
PHZLMBHDXVLRIX-UHFFFAOYSA-M
|
| InChi Code |
InChI=1S/C3H6O3.K/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
|
| Chemical Name |
potassium;2-hydroxypropanoate
|
| Synonyms |
POTASSIUM LACTATE; 996-31-6; Potassium DL-lactate; potassium 2-hydroxypropanoate; Monopotassium lactate; Lactic acid, potassium salt; Monopotassium 2-hydroxypropanoate; potassium;2-hydroxypropanoate;
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.8021 mL | 39.0107 mL | 78.0214 mL | |
| 5 mM | 1.5604 mL | 7.8021 mL | 15.6043 mL | |
| 10 mM | 0.7802 mL | 3.9011 mL | 7.8021 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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