Size | Price | Stock | Qty |
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50mg |
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100mg |
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250mg |
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500mg |
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1g |
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2g |
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5g |
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Other Sizes |
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Purity: ≥98%
Tianeptine sodium (Stablon, Coaxil, Tianeurax, Tatinol, Salymbra), the sodium salt of tianeptine and an atypical antidepressant, is a potent and selective serotonin reuptake enhancer (SSRE) used primarily for the treatment of major depressive disorders. In addition, it can be used to treat other symptoms like irritable bowel syndrome or asthma. Although tianeptine is chemically a tricyclic antidepressant (TCA), its pharmacological characteristics differ from those of typical TCAs due to recent research suggesting that tianeptine affects neural plasticity by indirectly altering glutamate receptor activity (i.e., AMPA and NMDA receptors) and releasing BDNF.
ln Vitro |
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ln Vivo |
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Animal Protocol |
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References |
Molecular Formula |
C21H24CLN2NAO4S
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Molecular Weight |
458.93
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Exact Mass |
436.12
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Elemental Analysis |
C, 54.96; H, 5.27; Cl, 7.72; N, 6.10; Na, 5.01; O, 13.94; S, 6.99
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CAS # |
30123-17-2
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Appearance |
Solid powder
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SMILES |
CN1C2=CC=CC=C2C(C3=C(S1(=O)=O)C=C(C=C3)Cl)NCCCCCCC(=O)[O-].[Na+]
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InChi Key |
ZLBSUOGMZDXYKE-UHFFFAOYSA-M
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InChi Code |
InChI=1S/C21H25ClN2O4S.Na/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);/q;+1/p-1
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Chemical Name |
sodium;7-[(3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl)amino]heptanoate
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Synonyms |
Tianeptine; brand names: Tatinol; Tianeurax; Salymbra; Stablon; Coaxil
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HS Tariff Code |
2934.99.9001
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 2.1790 mL | 10.8949 mL | 21.7898 mL | |
5 mM | 0.4358 mL | 2.1790 mL | 4.3580 mL | |
10 mM | 0.2179 mL | 1.0895 mL | 2.1790 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
NCT04249596 | Recruiting | Drug: Tianeptine Sodium | Treatment Resistant Depression | New York State Psychiatric Institute |
October 14, 2020 | Phase 4 |