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    TC 5115
    TC 5115

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V2198
    CAS #: N/APurity ≥98%

    Description: TC 5115(TC-5115) is a novel and potent inhibitor of MLL methyltransferase with IC50 value of 16 nM. TC-5115 may lead to the development of a new therapy for the treatment of human MLL leukemia. The mixed-lineage leukemia (MLL) protein, also known as MLL1, is a lysine methyltransferase specifically responsible for methylation of histone 3 lysine 4. MLL has been pursued as an attractive therapeutic target for the treatment of acute leukemia carrying the MLL fusion gene or MLL leukemia.

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    Molecular Formula: C23H32N8O5S
    Exact Mass: 532.2216
    Molecular Weight: 532.62
    Elemental Analysis: C, 51.87; H, 6.06; N, 21.04; O, 15.02; S, 6.02

    Synonym:  TC 5115;TC-5115; TC5115; 

    Chemical Name: (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)((1-(thiophen-2-ylmethyl)azetidin-3-yl)methyl)amino)butanoic acid

    InChi Key: KJOQVBZBXKPYJX-XVZIYINBSA-N

    InChi Code: InChI=1S/C23H32N8O5S/c24-15(23(34)35)3-4-29(6-13-7-30(8-13)9-14-2-1-5-37-14)10-16-18(32)19(33)22(36-16)31-12-28-17-20(25)26-11-27-21(17)31/h1-2,5,11-13,15-16,18-19,22,32-33H,3-4,6-10,24H2,(H,34,35)(H2,25,26,27)/t15-,16+,18+,19+,22+/m0/s1

    SMILES Code: O=C(O)[[email protected]@H](N)CCN(C[[email protected]]1O[[email protected]@H](N2C=NC3=C(N)N=CN=C23)[[email protected]](O)[[email protected]@H]1O)CC4CN(CC5=CC=CS5)C4


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