My cart
In the shopping cart is not goods, to choose and buy!
  • Product Name
  • Size
  • Quantity
  • Amount
    Selected items : 0 pieces Total : CHECK OUT()
    SYR-127063
    SYR-127063

    Price:
    Market Price:

    This product is for research use only, not for human use. We do not sell to patients.
    Number: - + Pieces(InventoryPieces)
    InvivoChem Cat #: V4588
    CAS #: 871026-18-5Purity ≥98%

    Description: SYR127063 (also known as BDBM92454) is a novel, potent and selective HER2 inhibitor with IC50 of 11 nM, 429 nM, > 10000 nM for HER2, EGFR, and HER4, respectively. SYR127063 binds to the active conformation of HER2.

    References: J Biol Chem. 2011 May 27;286(21):18756-65. 


    Customer Validation
    Official Supplier of
    • VE
    • OF
    • YALE
    • hhmi
    • 香港大学
    Related Products
    Publications Citing InvivoChem Products
    • Physicochemical and Storage Information
    • Protocol
    • Quality Control Documentation
    • Related Biological Data
    • Customer Review

    SYR-127063

    Name: SYR127063
    CAS#: 871026-18-5
    Chemical Formula: C23H20ClF3N4O3
    Exact Mass: 492.1176
    Molecular Weight: 492.8832
    Elemental Analysis: C, 56.05; H, 4.09; Cl, 7.19; F, 11.56; N, 11.37; O, 9.74
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: SYR127063; SYR-127063; SYR 127063; BDBM92454; BDBM-92454; BDBM 92454.
    IUPAC/Chemical Name: 2-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)ethoxy)ethan-1-ol
    InChi Key: CMMUJJHJYMYOJR-UHFFFAOYSA-N
    InChi Code: InChI=1S/C23H20ClF3N4O3/c24-18-13-16(4-5-20(18)34-17-3-1-2-15(12-17)23(25,26)27)30-22-21-19(28-14-29-22)6-7-31(21)8-10-33-11-9-32/h1-7,12-14,32H,8-11H2,(H,28,29,30)
    SMILES Code: FC(C1=CC(OC2=CC=C(NC3=C4N(C=CC4=NC=N3)CCOCCO)C=C2Cl)=CC=C1)(F)F


    • Molarity Calculator
    • Dilution Calculator
    • The molarity calculator equation

      Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

      • Mass
      • Concentration
      • Volume
      • Molecular Weight *
      • =
      • ×
      • ×
    • The dilution calculator equation

      Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

      This equation is commonly abbreviated as: C1V1 = C2V2

      • Concentration (start)
      • ×
      • Volume (start)
      • =
      • Concentration (final)
      • ×
      • Volume (final)
      • ×
      • =
      • ×
      • C1
      •  
      • V1
      •  
      • C2
      •  
      • V2

    These protocols are for reference only. InvivoChem does not independently validate these methods.

    评论

      Home Prev Next Last page / pices

      发评论

      ×
      Your information is safe with us. * Required Fields.
      Products are for research use only;  We do not sell to patients
      Tel: 1-708-310-1919
      Fax: 1-708-557-7486
      Subscribe to our E-newsletter
      • Name*
      • *
      • E-mail*
      • *
      • instructions:
      • *
      Copyright 2020 InvivoChem LLC | All Rights Reserved
      prompt
      Do you confirm the receipt?