| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
| ln Vitro |
Ebselen derivative 1 (Compound 19) (100 μM) significantly reduced cisplatin-induced apoptosis and ferroptosis in hair cells and alleviated the surge in oxidative stress triggered by cisplatin in the entire cochlea [1].
|
|---|---|
| ln Vivo |
Ebselen derivative 1 (Compound 19) (80 mg/kg; oral; once a day for one week) has a hearing-protective effect in C57BL/6 mice and can alleviate cisplatin (5 mg/kg; intraperitoneal injection; once on the third and seventh days of Ebselen derivative 1 administration)-induced hair cell loss [1].
|
| References |
| Molecular Formula |
C13H10N2O2SE
|
|---|---|
| Molecular Weight |
305.19
|
| CAS # |
3030492-59-9
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.2766 mL | 16.3832 mL | 32.7665 mL | |
| 5 mM | 0.6553 mL | 3.2766 mL | 6.5533 mL | |
| 10 mM | 0.3277 mL | 1.6383 mL | 3.2766 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
