Size | Price | Stock | Qty |
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1mg |
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5mg |
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10mg |
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Other Sizes |
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ln Vitro |
On days 5, 7, and 9, respectively, (Sar1)-Angiotensin II (1 μM/day; 9 days) raised the total protein content in embryonic chicken myocytes by 18.5, 26.2, and 22.2% [2]. Cynomolgus monkey brain meningeal-rich granules bind to (Sar1)-angiotensin II with a Kd of 2.7 nM [3].
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References |
[1]. Matsoukas JM, et, al. Differences in backbone structure between angiotensin II agonists and type I antagonists. J Med Chem. 1995 Nov 10;38(23):4660-9.
[2]. Aceto JF, et, al. [Sar1]angiotensin II receptor-mediated stimulation of protein synthesis in chick heart cells. Am J Physiol. 1990 Mar;258(3 Pt 2):H806-13. [3]. Millan MA, et, al. Distribution of angiotensin II receptors in the brain of nonhuman primates. Peptides. Mar-Apr 1990;11(2):243-53. |
Molecular Formula |
C49H71N13O10
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Molecular Weight |
1002.16914
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CAS # |
51833-69-3
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SMILES |
N/C(=N/CCCC(C(NC(C(NC(C(NC(C(NC(C(N1CCCC1C(NC(CC1=CC=CC=C1)C(=O)O)=O)=O)CC1=CN=CN1)=O)C(CC)C)=O)CC1=CC=C(O)C=C1)=O)C(C)C)=O)NC(CNC)=O)/N
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 0.9978 mL | 4.9892 mL | 9.9783 mL | |
5 mM | 0.1996 mL | 0.9978 mL | 1.9957 mL | |
10 mM | 0.0998 mL | 0.4989 mL | 0.9978 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.