| Size | Price | Stock | Qty |
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| 50mg |
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| 100mg |
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| 250mg | |||
| Other Sizes |
| Targets |
S-(2-Carboxyethyl)-L-cysteine does not have a specific pharmacological target. It is a metabolite and a cysteine derivative that may be involved in metabolic and antioxidant pathways. It can be used to study cellular processes involving cysteine, such as redox regulation and protein synthesis. Its mechanism of action is based on its role as a cysteine analog, which can be incorporated into metabolic pathways.
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| ln Vitro |
In vitro, S-(2-Carboxyethyl)-L-cysteine is used in research to study cellular processes involving cysteine. It may be involved in metabolic and antioxidant pathways. Specific activity data, such as IC50 values, are not applicable as it is a metabolite rather than a pharmacologically active compound.
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| ln Vivo |
S-(2-carboxyethyl)-L-cysteine dramatically raises plasma urea levels in rats [1].
In vivo, S-(2-Carboxyethyl)-L-cysteine is a naturally occurring metabolite. It is not used as a therapeutic agent. Its presence in biological samples can be measured as an indicator of cysteine metabolism. |
| Enzyme Assay |
A cell-free assay for S-(2-Carboxyethyl)-L-cysteine is not applicable as it is not an enzyme inhibitor. Its properties as a metabolite can be characterized by standard analytical techniques. It can be used as a standard in assays measuring cysteine metabolites.
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| Cell Assay |
Cellular experiments with S-(2-Carboxyethyl)-L-cysteine would typically involve studying its effects on cellular redox status or protein synthesis. Cells are treated with the compound, and markers of oxidative stress or protein synthesis are measured. Specific protocols are not detailed.
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| Animal Protocol |
In vivo animal experiments for S-(2-Carboxyethyl)-L-cysteine are not described in the available sources. As a metabolite, it could be used as a biomarker in studies of cysteine metabolism. However, no specific protocols or data are provided.
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| ADME/Pharmacokinetics |
S-(2-Carboxyethyl)-L-cysteine has a molecular formula of C6H11NO4S and a molecular weight of 193.22 g/mol. Its CAS number is 4033-46-9. It is a solid. It has a purity of >98.0%. For storage, it should be kept at room temperature in a cool, dark place. Specific pharmacokinetic properties are not applicable as it is not a therapeutic drug.
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| Toxicity/Toxicokinetics |
Toxicity data for S-(2-Carboxyethyl)-L-cysteine are not provided in the available sources. As a metabolite, it is generally considered to have low toxicity. However, specific toxicological information is not available. It is intended for research use only and is not for human consumption.
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| References |
[1]. Falade OS, et al. S-Carboxyethylcysteine (a constituent of Acacia seed) negatively affects casein protein utilization by rats. Nutrition. 2012 Jul;28(7-8):785-92.
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| Additional Infomation |
According to reports, S-(2-carboxyethyl)-L-cysteine has been found in plants of the Acacia genus, and relevant data are available for reference.
S-(2-Carboxyethyl)-L-cysteine (CAS: 4033-46-9) is a metabolite of cysteine. Its synonyms include SCE and 3-[(2-Carboxyethyl)thio]alanine. The compound is used in research to study cellular processes involving cysteine. It is not a therapeutic drug and is strictly for research purposes. |
| Molecular Formula |
C6H11NO4S
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|---|---|
| Molecular Weight |
193.2208
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| Exact Mass |
193.04
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| CAS # |
4033-46-9
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| PubChem CID |
23618202
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.4±0.1 g/cm3
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| Boiling Point |
436.5±45.0 °C at 760 mmHg
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| Melting Point |
218°C
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| Flash Point |
217.8±28.7 °C
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| Vapour Pressure |
0.0±2.2 mmHg at 25°C
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| Index of Refraction |
1.573
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| LogP |
0.08
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| Hydrogen Bond Donor Count |
3
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| Hydrogen Bond Acceptor Count |
6
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| Rotatable Bond Count |
6
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| Heavy Atom Count |
12
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| Complexity |
173
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| Defined Atom Stereocenter Count |
1
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| SMILES |
S(C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])[C@@]([H])(C(=O)O[H])N([H])[H]
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| InChi Key |
FBPINGSGHKXIQA-BYPYZUCNSA-N
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| InChi Code |
InChI=1S/C6H11NO4S/c7-4(6(10)11)3-12-2-1-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
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| Chemical Name |
(2R)-2-amino-3-(2-carboxyethylsulfanyl)propanoic acid
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O : ~5 mg/mL (~25.88 mM)
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| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.1754 mL | 25.8772 mL | 51.7545 mL | |
| 5 mM | 1.0351 mL | 5.1754 mL | 10.3509 mL | |
| 10 mM | 0.5175 mL | 2.5877 mL | 5.1754 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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