| Size | Price | Stock | Qty |
|---|---|---|---|
| 250mg |
|
||
| Other Sizes |
| ADME/Pharmacokinetics |
Absorption, Distribution and Excretion
Samples were collected from the liver, heart, kidneys, muscle, and adipose tissue (perirhinal and subcutaneous) of six cattle for hydrocarbon composition analysis. Qualitative and quantitative analyses were performed using gas chromatography and gas chromatography-mass spectrometry. Despite varying proportions, a series of homologous n-alkanes with carbon chain lengths ranging from n-C12 to n-C31 were found in all samples. Additionally, isoprene hydrocarbons phytane and phyene (phytane-1 and phyene-2) were identified. (These findings are highly relevant to human health from consuming hydrocarbon-contaminated meat.) /n-Alkanes/ |
|---|---|
| Toxicity/Toxicokinetics |
Toxicity Summary
Identification and Uses: Nonadecane is a solid n-alkane containing 19 carbon atoms (C19). Solid n-alkanes (paraffin) have a wide range of uses: they can be used as feedstock in gasoline blending and in oxidation and chlorination reactions. Human Exposure and Toxicity: No relevant data are currently available. Animal Studies: A series of homologous n-alkanes with carbon chain lengths ranging from n-C12 to n-C31 were found in all bovine tissue samples. Ecotoxicity Studies: Volatile organic compounds released from the flowers of A. dealbata (comprising heptadecane, n-nonadecane, n-trisane, and octadecene, accounting for 62% of the composition) strongly inhibited seed germination and seedling growth in this specific species, particularly its own seedlings. |
| References | |
| Additional Infomation |
Wax. (NTP, 1992)
Noctodecane is a straight-chain alkane containing 19 carbon atoms. It was once found to be a component of Artemisia armeniaca essential oil. It is a plant metabolite and volatile oil component. Noctodecane has also been reported in tea tree (Camellia sinensis), Madagascar vanilla (Vanilla madagascariensis), and several other organisms with relevant data. See also: Moringa leaf oil (partial). |
| Molecular Formula |
C19H40
|
|---|---|
| Molecular Weight |
268.52
|
| Exact Mass |
268.313
|
| CAS # |
629-92-5
|
| PubChem CID |
12401
|
| Appearance |
Waxy solid
Leaflets White solidified mass or fragments |
| Density |
0.786 g/mL at 25 °C(lit.)
|
| Boiling Point |
330 °C(lit.)
|
| Melting Point |
89.8 °F (NTP, 1992)
; Melting point equals 90 °F
; 31.50 °C
; 32 °C
|
| Flash Point |
335 °F
|
| Vapour Pressure |
1 mm Hg ( 133.2 °C)
|
| Index of Refraction |
1.4410
|
| Source |
Originated from plants: Cactaceae Opuntia littoralis (Engelm.) Britton & Rose
|
| LogP |
7.657
|
| Hydrogen Bond Donor Count |
0
|
| Hydrogen Bond Acceptor Count |
0
|
| Rotatable Bond Count |
16
|
| Heavy Atom Count |
19
|
| Complexity |
123
|
| Defined Atom Stereocenter Count |
0
|
| SMILES |
C([H])([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
|
| InChi Key |
LQERIDTXQFOHKA-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C19H40/c1-3-5-7-9-11-13-15-17-19-18-16-14-12-10-8-6-4-2/h3-19H2,1-2H3
|
| Chemical Name |
nonadecane
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.7241 mL | 18.6206 mL | 37.2412 mL | |
| 5 mM | 0.7448 mL | 3.7241 mL | 7.4482 mL | |
| 10 mM | 0.3724 mL | 1.8621 mL | 3.7241 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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